Search for dissertations about: "colorimetric assay"

Showing result 1 - 5 of 11 swedish dissertations containing the words colorimetric assay.

2. 1. Effects of Dehydration and Blockade of the Renin-Angiotensin System in the One-humped Camel (Camelus dromedarius)

   Author : Mahmoud Al Haj; Fred Nyberg; Santi Spampinato; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Blood; biochemical analysis; catecholamine; colorimetric assay; cortisol; dehydration; dromedary camel; glutathione; hematological analysis; HPLC; insulin- like growth factor-1; losartan; plasma; receptors; radioimmunoassay; serum; Pharmaceutical Science; Farmaceutisk vetenskap;

   Abstract : The one-humped or the dromedarian camel is a pseudo-ruminant mammal, well adapted to the hot and dry climates of the desert. Its ability to withstand torrid heat and extreme desiccation is of paramount importance to its survival. READ MORE

4. 2. Novel planar and particle-based microarrays for point-of-care diagnostics

   Author : Gustav Svedberg; Helene Svahn Andersson; Jesper Gantelius; Fridtjof Lund-Johansen; KTH; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Planar microarrays; Particle-based microarrays; Point-of-care diagnostics; Colorimetric detection; Signal enhancement; Isothermal DNA amplification; Solid-phase DNA amplification; Biotechnology; Bioteknologi;

   Abstract : Point-of-care assays are easy-to-use, portable and inexpensive tests that canbe used to aid diagnostics by measuring levels of disease-specific moleculesin settings where access to advanced laboratory equipment and trainedpersonnel are limited, such as at the patient's bedside or in low resourceparts of developing countries. In order to achieve high multiplexingcapacities, such assays can be based on planar microarrays consisting ofspots immobilized on a flat surface or on particle-based microarrays basedon populations of encoded particles. READ MORE

5. 3. Detection and Sequencing of Amplified Single Molecules

   Author : Rongqin Ke; Mats Nilsson; Ulf Landegren; Radoje Drmanac; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; padlock probes; proximity ligation assay; rolling circle amplification; circle-to-circle amplification; single molecule detection; amplified single molecules; sequencing; in situ; single cell; Molecular Biotechnology; Molekylär bioteknik;

   Abstract : Improved analytical methods provide new opportunities for both biological research and medical applications. This thesis describes several novel molecular techniques for nucleic acid and protein analysis based on detection or sequencing of amplified single molecules (ASMs). READ MORE

6. 4. Novel methods for improving rapid paper-based protein assays with gold nanoparticle detection

   Author : Lara Lama; Helene Andersson Svahn; Jesper Gantelius; KTH; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Gold nanoparticles; ultrasound energy; signal enhancement; diagnostics; microarrays; paper-based assays; COMSOL Multiphysics simulations; Bioteknologi; Biotechnology;

   Abstract : This thesis describes methods for improving sensitivity in rapid singleplex and multiplex microarray assays. The assays utilize the optical characteristics of colloidal gold nanoparticles for the colorimetric detection of proteins.Multiplexed detection in sandwich immunoassays is limited by cross-reactivity between different detection antibodies. READ MORE

7. 5. In vitro testing of drug sensitivity in tumor cells from effusion

   Author : Carl-Olof Hillerdal; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Malignant mesothelioma has a mean overall survival of around 1 year and lung adenocarcinoma with pleural spread has a mean overall survival of around 5 months. Both diseases cause fluid accumulation in the pleura, which is drained to alleviate associated symptoms such as shortness of breath. This fluid oft contains exfoliated tumor cells. READ MORE