Search for dissertations about: "complement system"
Showing result 6 - 10 of 507 swedish dissertations containing the words complement system.
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6. The Role of IgM and Complement in Antibody Responses
Abstract : An intact complement system including the complement receptors 1 and 2 (CR1/2) is crucial for the generation of a normal antibody response in animals and humans. Moreover, activation of the classical pathway is thought to be important since deficiency in complement components C1q, C2, C4 or C3 lead to impaired antibody responses. READ MORE
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7. The role of the complement system in arthritis and stroke
Abstract : Complement is part of the innate immune system and functions primarily as a first line of defense against invading microorganisms. It is a complex cascade, which can be activated via three pathways: the classical, alternative and mannan-binding lectin pathway. READ MORE
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8. Complement Activation Triggered by Biomaterial Surfaces : Mechanisms and Regulation
Abstract : Today there are a vast number of medical devices in temporary or permanent contact with human tissues. Blood-biomaterial contact is known to trigger the complement system and results in generation of fluid phase anaphylatoxins C3a and C5a, and surface-bound C3b and iC3b. READ MORE
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9. Complement aberrations and autoantibodies to complement proteins in relation to disease mechanisms
Abstract : The complement system, a part of the innate immune system with several links to the adaptive immune system, plays an important role in the pathogenesis of many diseases. The purpose of this thesis was to document and clarify some of these mechanisms. The thesis is based on four papers (I-IV). READ MORE
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10. The role of the complement system in basal and ischemia-induced neurogenesis
Abstract : .... READ MORE