Search for dissertations about: "correlation methods"

Showing result 1 - 5 of 1344 swedish dissertations containing the words correlation methods.

2. 1. Integrating Efficacy and Toxicity in Preclinical Anticancer Drug Development : Methods and Applications

   Author : Caroline Haglund; Elin Lindhagen; Rolf Larsson; Anna Åleskog; Sigurd Vitols; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anticancer drugs; In vitro assays; Toxicity testing; Haematological toxicity; Primary tumour cells; Species difference; Clinical pharmacology; Klinisk farmakologi; Clinical Pharmacology; Klinisk farmakologi;

   Abstract : Preclinical testing is an important part of cancer drug development. The aim of this thesis was to establish and evaluate preclinical in vitro methods useful in the development of new anticancer drugs. In paper I, the development of non-clonogenic assays (FMCA-GM) using CD34+ stem cells for assessment of haematological toxicity was described. READ MORE

4. 2. Correlated materials : models and methods

   Author : Hugo Strand; Göteborgs universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; correlated electrons; Hubbard model; multiband Hubbard model; dynamical mean field theory; exact diagonalization; Landau theory; Mott metal-insulator transition; Gutzwiller method; many-body point group symmetry; ironchalcogenides; Kanamori interaction; Slater-Condon interaction;

   Abstract : This thesis encompass a series of studies on methods and models for electron systems with local interactions, relevant for correlated materials. The first study focus on the canonical model for local correlation, the Hubbard model. READ MORE

5. 3. Assessment of central auditory functions : methods and applications

   Author : Mathias Hällgren; Linköpings universitet; []
   Keywords : MEDICINE; MEDICIN;

   Abstract : Central auditory processing is complex and can not be completely evaluated by a single method. This thesis focuses on assessment of some aspects of central auditory functions by the use of dichotic speech tests, cognitive tests that tax functions important for speech processing and electrophysiological tests. READ MORE

6. 4. Evaluation of a Miniaturized Rotating Disk Apparatus for In Vitro Dissolution Rate Measurements in Aqueous Media : Correlation of In Vitro Dissolution Rate with Apparent Solubility

   Author : Anita M. Persson; Curt Pettersson; Anders Sokolowski; Anders Karlsson; Alex Avdeef; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; analytical methods; HPLC high-performance liquid chromatography ; miniaturization; in vitro dissolution rate; apparent solubility; physicochemical properties; dissolution media; correlation study; chemometrics; Pharmaceutical chemistry; Farmaceutisk kemi; Analytical Pharmaceutical Chemistry; Analytisk farmaceutisk kemi;

   Abstract : The general aim of this thesis was to evaluate a newly designed and constructed miniaturized rotating disk apparatus for in vitro dissolution rate measurements of different drug substances from all of the classes in the Biopharmaceutical Classification System (BCS). The new equipment is based on a low volume flow-through cell of Plexiglas, a gold plated magnetic bar and a special designed press. READ MORE

7. 5. Electronic transitions and correlation effects : From pure elements to complex materials

   Author : Johan Jönsson; Igor A. Abrikosov; Marcus Ekholm; Sergei Dudarev; Linköpings universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Electronic transition; solid state physics; condensed matter physics; correlation effects;

   Abstract : Macroscopic properties of real materials, such as conductivity, magneticproperties, crystal structure parameters, etc. are closely related or evendetermined by the configuration of their electrons, characterized by electronicstructure. By changing the conditions, e.g, pressure, temperature, magnetic/electric field, chemical doping, etc. READ MORE