Search for dissertations about: "cox model"

Showing result 1 - 5 of 161 swedish dissertations containing the words cox model.

  2. 1. Neuropeptide Y Receptors in Human, Guinea pig and Chicken : Cloning, in vitro Pharmacology and in situ Hybridization

    Author : Sara Holmberg; Helen Cox; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; G-protein coupled receptor; neuropeptide Y; neuropeptide Y receptor; ortholog; chicken; guinea pig; mutagenesis; receptor computer modeling; mRNA in situ hybridization; Neurovetenskap; Neurology; Neurologi; medicinsk farmakologi; Medical Pharmacology;

    Abstract : Neuropeptide Y (NPY) is known to influence a vast number of physiological and behavioral processes such as vasoconstriction, circadian rhythms, feeding, anxiety and memory. Peptides of the NPY family bind to five different cloned G-protein coupled receptor subtypes (Y1, 2, 4-6). READ MORE

  4. 2. Optimal Design and Inference for Correlated Bernoulli Variables using a Simplified Cox Model

    Author : Daniel Bruce; Hans Nyquist; Werner G. Müller; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cox binary model; correlated binary data; log-odds ratio; D-optimality; E-optimality; power maximization; efficiency; Statistics; Statistik; statistik; Statistics;

    Abstract : This thesis proposes a simplification of the model for dependent Bernoulli variables presented in Cox and Snell (1989). The simplified model, referred to as the simplified Cox model, is developed for identically distributed and dependent Bernoulli variables. READ MORE

  5. 3. Establishment and characterization of a murine T-cell lymphoma/leukemia model

    Author : Ann-Sofie Johansson; Dan Holmberg; Magnus Lindskog; Finn Skou Pedersen; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mouse model; T-cell lymphoma; Moloney murine leukemia virus; proviral integration; lymphomagenesis; COX-2; omega 3; Oncology; Onkologi; onkologi; Oncology;

    Abstract : Mouse models of human disease are valuable tools for studying pathogenesis and for evaluating novel therapies. T-cell lymphoma is a relatively rare disease in humans, affecting 100-150 persons yearly in Sweden. It exists in both aggressive and more indolent forms. READ MORE

  6. 4. Essays on the Assumption of Proportional Hazards in Cox Regression

    Author : Inger Persson; Kenneth Carling; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Informatics; computer and systems science; Proportional hazards; Cox regression; Proportionality assumption; Informatik; data- och systemvetenskap; Informatics; computer and systems science; Informatik; data- och systemvetenskap; statistik; Statistics;

    Abstract : This thesis consists of four papers about the assumption of proportional hazards for the Cox model in survival analysis. The first paper compares the hazard ratio estimated from the Cox model to an exact calculation of the geometric average of the hazard ratio when the underlying assumption of proportional hazards is false, i.e. READ MORE

  7. 5. Essays on Social Capital, Health and Socioeconomic Inequalities in Health A Health Economic Study

    Author : Kamrul Islam; Socialepidemiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; economic systems; economic theory; Economics; econometrics; Samhällsvetenskaper; Social sciences; epidemiologi; Folkhälsa; epidemiology; Public health; Sweden; Panel data fixed-effect model; Decomposition analysis; Concentration index; Socioeconomic health inequality; Population aging; Survival analysis; Extended Cox model; Multilevel analysis; Unbalanced panel data; Externalities; Crime rates; Election participation rates; Community social capital; Municipality-level social capital; Systematic review; Egalitarianism; Determinants of health; Mortality; Health-related quality of life; Health; Keywords; Social capital; economic policy; Nationalekonomi; ekonometri; ekonomisk teori; ekonomiska system; ekonomisk politik;

    Abstract : The thesis comprises four independent research papers and a summary that focus on two related dimensions. The first dimension focuses on the understanding of the production of health. Particularly, the question is asked whether community's stock of social capital influence individual's health. READ MORE