Search for dissertations about: "cryptococcus"

Showing result 1 - 5 of 13 swedish dissertations containing the word cryptococcus.

  2. 1. Alveolar macrophages and lung surfactant in the defense against Cryptococcus neoformans

    Author : Norma Teresa Gross; Karolinska Institutet; Karolinska Institutet; []
    Keywords : alveolar macrophages; Cryptococcus neoformans; lung surfactant;

    Abstract : Cryptococcus neoformans causes disease mainly in immunosuppressed patients, especially those with AIDS, and on corticosteroids. The yeast is normally inhaled and the lung is the primary site of infection, where the alveolar macrophages (AM) provide a first line of host defense. READ MORE

  4. 2. Bark lesions and sensitivity to frost in beech and Norway spruce

    Author : Anna Maria Jönsson; Institutionen för naturgeografi och ekosystemvetenskap; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Picea abies; Multiple stress; Mineral nutrient balance; Liming; Lichen indices; Fagus sylvatica; Cryptococcus fagisuga; Excess nitrogen; Vitality fertilization; Plant ecology; Växtekologi;

    Abstract : Strong temperature fluctuations and pathogen attacks can cause bark lesions, visible signs of wounds in the phloem and cambium. Pathogenic insects and fungi are able to invade lesions that have not healed, further increasing the damage. READ MORE

  5. 3. Synthesis of oligosaccharides related to the capsular polysaccharides of Cryptococcus neoformans

    Author : Lars Olsson; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : .... READ MORE

  6. 4. Synthesis of oligosaccharides related to the capsular polysaccharides of Streptococcus pneumoniae serotype 9 and of Cryptococcus neoformans

    Author : Marianne Alpe; Ulf Ellervik; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Organisk kemi; Organic Chemistry; organisk kemi;

    Abstract : In the present investigation, synthesis of oligosaccharides corresponding to structural elements present in the capsular polysaccharides of Streptococcus pneumoniae and Cryptococcus neoformans has been achieved. The first two sections describe the synthesis of spacer-equipped oligosaccharides corresponding to structures from the CPS of Streptococcus pneumoniae serotypes 9N, 9A and 9L, the production of which involved synthetic challenges such as the construction of β-ManNAc and α-GlcA linkages. READ MORE

  7. 5. Development of strategies for construction of thioglycoside building blocks corresponding to repeating triads of Cryptococcus neoformans GXM capsular polysaccharide

    Author : Lina Rydner; Stefan Oscarson; Olof Ramström; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Crytococcus neoformans; Capsular polysaccharide; Thioglycosides; Convergent synthesis; Organic chemistry; Organisk kemi; organisk kemi; Organic Chemistry;

    Abstract : This thesis focuses on the development of methods for synthesis of thioglycoside building blocks corresponding to the repeating units of the capsular polysaccharide (CPS) of Cryptococcus neoformans, an opportunistic fungal pathogen. The building blocks are suitable for construction of large synthetic oligosaccharides related to the native CPS-structures which are to be used in biological studies in order to identify protective epitopes with the aim to develop a glycoconjugate vaccine against C. READ MORE