Search for dissertations about: "crystallin"

Showing result 1 - 5 of 18 swedish dissertations containing the word crystallin.

  2. 1. The Human Endometrium : Studies on Angiogenesis and Endometriosis

    Author : Christian Moberg; Matts Olovsson; Anneli Stavreus-Evers; Lalit Kumar Parameswaran Grace; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; endometrium; angiogenesis; endothelial cell; endometriosis; receptivity; implantation; oestrogen receptor; progesterone receptor; crystallin; interleukin; vasoactive intestinal peptide; peritoneal fluid; Obstetrik och gynekologi; Obstetrics and Gynaecology;

    Abstract : Angiogenesis is thought to play a pivotal role in the cycling endometrium. Coordinated by oestrogen and progesterone, endometrial blood vessel development is primarily mediated by vascular endothelial growth factor-A (VEGF-A), which promotes endothelial cell (EC) proliferation and protects ECs from induced apoptosis. READ MORE

  4. 2. Molecular and epidemiological studies on eyes with pseudoexfoliation syndrome

    Author : Amelie Botling Taube; Jonas Bergquist; Albert Alm; Eva Larsson; Hannu Uusitalo; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pseduoexfoliation syndrome; PEX; aqueous humor; cataract; cataract surgery; lens capsule; proteomics; mass spectrometry; MS; MALDI TOF MS MS; quantitative proteomics; iTRAQ; dimethyl labeling; imaging mass spectrometry; IMS; time of flight secondary ion mass spectrometry; TOF-SIMS; crystallin; epidemiology; risk factor; Ophtalmology; Oftalmiatrik;

    Abstract : Pseudoexfoliation (PEX) syndrome is an age-related condition characterized by the production and accumulation of extracellular fibrillary material in the anterior segment of the eye. PEX predisposes for several pathological conditions, such as glaucoma and complications during and after cataract surgery. READ MORE

  5. 3. Molecular Regulation of Inflammation and Angiogenesis in the Tumor Microenvironment

    Author : Lothar Dieterich; Anna Dimberg; Lena Claesson-Welsh; Jonas Fuxe; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; stroma; glioma; alphaB-crystallin; HSPB5; cryab; myeloid cells; Morphology; cell biology; pathology; Morfologi; cellbiologi; patologi; Cell and molecular biology; Cell- och molekylärbiologi; Molekylär medicin; Molecular Medicine;

    Abstract : Tumor growth and progression not only depend on properties of the malignant cells but are strongly influenced by the tumor microenvironment. The tumor stroma consists of various cell types such as inflammatory cells, endothelial cells and fibroblasts, which can either inhibit or promote tumor growth. READ MORE

  6. 4. Endothelial activation and inflammation in the tumor microenvironment

    Author : Hua Huang; Anna Dimberg; William C. Aird; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tumor angiogenesis; endothelial activation; leukocyte recruitment; VEGF-A; αB-crystallin; ELTD1;

    Abstract : Tumors are composed not only of malignant cells, but also of various types of normal cells, including vascular cells and infiltrating immune cells, which drive tumor development and progression. The tumor vasculature is abnormal and dysfunctional due to sustained tumor angiogenesis driven by high levels of pro-angiogenic factors. READ MORE

  7. 5. A Chloroplast Localized Small Heat Shock Protein, Hsp21. Importance of Hsp21 in stress protection of transgenic Arabidopsis thaliana, recombinant expression and characterization of oxidation-dependent conformational changes

    Author : Ulrika Härndahl; Biokemi och Strukturbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; a-crystallin; sHsp; chaperone; amphipathic a-helix; oligomer; redox-regulated; methionine sulfoxidation; oxidative stress; regulation; protein structure; circular dichroism; mass spectrometry; fluorescence spectroscopy; Biochemistry; Metabolism; Biokemi;

    Abstract : A specific group of heat shock proteins, the so called small heat shock proteins (sHsps), exists in all organisms but are especially abundant in plants. The sHsps prevent aggregation of other proteins (substrate proteins) during transient heat and oxidative stress. READ MORE