Search for dissertations about: "cultured cells"

Showing result 21 - 25 of 691 swedish dissertations containing the words cultured cells.

  2. 21. The role of glial cells in alpha-synuclein pathology : Focus on degradation, cell-to-cell propagation and inflammation

    Author : Jinar Rostami; Anna Erlandsson; Martin Ingelsson; Joakim Bergström; Michael Heneka; Uppsala universitet; []
    Keywords : Parkinson’s disease; alpha-synuclein; amyloid-beta; astrocytes; microglia; tunneling nanotubes; antigen presentation; T cells; glial crosstalk; degradation; KYP-2407; Medicinsk vetenskap; Medical Science;

    Abstract : Growing evidence emphasizes the role of astrocytes and microglia in Parkinson’s disease (PD) and Alzheimer’s disease (AD). Yet, little is known about their impact on specific disease processes and if their involvement is beneficial or detrimental. READ MORE

  4. 22. Mitotic aberrations in mammalian cells

    Author : Anna Renglin Lindh; Thomas Helleday; Micheline Kirsch-Volders; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; aneuploidy; mitotic aberrations; chemical effects; human cancer; DNA repair; Genetics; Genetik;

    Abstract : Almost all cancer cells are aneuploid showing the wrong chromosome number and often with structural aberrations. The degree of aneuploidy correlates with an increase of the severity of the disease and tumour cells with chromosomal instability are more prone to acquire resistance to chemotherapy than other cells. READ MORE

  5. 23. Mast cells in bacterial infections

    Author : Elin Rönnberg; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Mast cells are implicated in immunity towards bacterial infection, but the molecular mechanisms by which mast cells contribute to the host response are only partially understood. Previous studies have examined how mast cells react to purified bacterial cell wall components, such as peptidoglycan and lipopolysaccharide. READ MORE

  6. 24. Human articular chondrocytes. Plasticity and differentiation potentials

    Author : Tommi Tallheden; Göteborgs universitet; []
    Keywords : autologous chondrocyte transplantation; dedifferentiation; redifferentiation; stem; cells;

    Abstract : Articular cartilage has no or very low ability for self-repair and untreated lesions may lead tothe development of Osteoarthritis (OA). One method, which has been proved to result in longterm repair of isolated lesions, is autologous chondrocyte transplantation (ACT). READ MORE

  7. 25. Regulation of apoptosis and steroidogenesis in ovarian preovulatory granulosa cells

    Author : Eva Svensson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; apoptosis; granulosa cells; luteinizing hormone; progesterone receptor; RU 486; Org 31710; leptin; steroidogenesis;

    Abstract : Only a minute fraction of ovarian follicles present in a foetal ovary will complete the path to ovulation. The majority of the follicles will instead undergo atresia, a hormonally controlled apoptotic process. Apoptosis occurs throughout follicle development, with an extensive reduction in the number of follicles present at birth. READ MORE