Search for dissertations about: "cyp17"
Showing result 1 - 5 of 10 swedish dissertations containing the word cyp17.
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1. Pharmacogenetic analysis in sickness and in health - for better or for worse
Abstract : An individual's pharmacogenetic constitution may predict response to drugs, hormones and toxins, and might be a susceptibility factor for disease. Pharmacogenetic diversity is especially pronounced for drug metabolising enzymes. READ MORE
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2. Genetic variation and prostate cancer : population-based association studies in Sweden
Abstract : Prostate cancer constitutes the most common malignancy and the most common cause of cancer‐related death in Swedish men. A large body of evidence suggests that inherited genetic variants contribute to both development and progression of prostate cancer. READ MORE
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3. Genetic polymorphisms, IGF-1, and oral contraceptive use in women from high-risk breast cancer families
Abstract : Breast cancer is the most common cancer among Swedish women, affecting more than 7000 women each year. About 5-10% of all breast cancers are hereditary, with a monogenic inheritance pattern, but only 2-4% are explained by germline mutations in BRCA1 or BRCA2. BRCA1/BRCA2 mutation carriers have a 60-80% risk of developing breast cancer. READ MORE
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4. Functional and diagnostic aspects on adrenocortical adenoma
Abstract : Adrenocortical tumours are frequently detected due to increased use of imaging techniques like computed tomography, magnetic resonance imaging or ultrasound. The majority of the patients have tumours that do not have any overproduction of hormone. READ MORE
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5. Hormonal and paracrine influences on Leydig cell steroidogenesis
Abstract : Androgen production by Leydig cells is critical for development of the male reproductive organs and for maintaining normal body homeostasis and fertility later in life. Biosynthesis of testosterone is driven by secretion of the gonadotropin, luteinizing hormone (LH) from the pituitary. READ MORE