Search for dissertations about: "cytogenetic"

Showing result 1 - 5 of 94 swedish dissertations containing the word cytogenetic.

  2. 1. CYTOGENETIC AND MOLECULAR GENETIC CHARACTERIZATION OF LIPOMAS

    Author : Hammurabi Bartuma; Avdelningen för klinisk genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; soft tissue tumors; adipocytic tumors; conventional lipomas; spindle cell lipoma; HMGA2; cytogenetic; molecular genetic; SNP array; GGE;

    Abstract : The focus of this thesis was to study cytogenetic and molecular genetic aberrations in lipomas. For this purpose, chromosome banding analysis, fluorescence in situ hybridization (FISH), as well as high resolution single nucleotide polymorphism (SNP)–arrays were used to identify recurrent chromosomal aberrations in lipomas. READ MORE

  4. 2. Genetic analyses of multiple myeloma and related plasma cell dyscrasias

    Author : Therese Nilsson; Avdelningen för klinisk genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetik; cytogenetik; cytogenetics; Genetics; FISH; cytogenetic; multiple myeloma; MGUS;

    Abstract : Acquired genetic changes have proved to be of diagnostic and prognostic importance in different hematologic malignancies as well as in some solid tumor types. However, although multiple myeloma (MM), an incurable disease, and its proceeding stage monoclonal gammopathy of undetermined significance (MGUS) are quite common, little is known about the karyotypic features of these plasma cell dyscrasias. READ MORE

  5. 3. Case-control studies on risk factors for myeloid leukemias and myelodysplastic syndromes

    Author : Jonas Björk; Avdelningen för arbets- och miljömedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; epidemiologic methods; bias epidemiology ; attributable fraction; smoking; hobbies; occupational exposure; chromosome aberrations; epidemiology; cytogenetic; Occupational health; industrial medicine; Yrkesmedicin; arbetsmiljömedicin;

    Abstract : Case-control studies comprising telephone interviews for 333 cases of acute myeloid leukemia (AML), 226 cases of Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML), 330 cases of myelodysplastic syndromes (MDS), and matched controls were conducted. Information had to be obtained from next-of-kin much more often for cases (85%) than for controls (18%). READ MORE

  6. 4. Cytogenetic studies of benign breast lesions

    Author : Catarina Lundin; Avdelningen för klinisk genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Clinical genetics; cancer risk; breast cancer; phyllodes tumor; papilloma; fibroadenoma; prophylactic mastectomies; fibrocystic lesions; Cytogenetics; chromosomes; Klinisk genetik; Cytology; oncology; cancerology; Cytologi; onkologi; cancer;

    Abstract : In the present thesis benign breast lesions of various histologies, i.e. READ MORE

  7. 5. Clinical - cytogenetic correlations in malignant hematologic disorders

    Author : Nils Mauritzson; Avdelningen för hematologi och transfusionsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematologi; extracellular fluids; Haematology; treatment-related.; prognosis; gender; age; morphology; Karyotype; hematologic malignancies; extracellulära vätskor; Cytology; oncology; cancerology; Cytologi; onkologi; cancer;

    Abstract : In the present thesis, clinicogenetic correlations are investigated in a large population-based series of acute myeloid leukemia (AML), myelodysplastic syndromes (MDS), acute lymphoblastic leukemia, and chronic myeloid leukemia, for which the karyotypes were analyzed at the same center. The karyotypic pattern, i.e. READ MORE