Search for dissertations about: "cytotoxic T cells"
Showing result 11 - 15 of 268 swedish dissertations containing the words cytotoxic T cells.
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11. CD19-targeting CAR T Cells for Treatment of B Cell Malignancies : From Bench to Bedside
Abstract : Immunotherapy for cancer is a young research field progressing at high speed. The first chimera of an antibody and a signaling chain was designed by Zelig Eshhar and was later further developed to enhance existing T cell therapy by combining a single-chain fragment of an antibody with the CD3 zeta chain of the TCR complex. READ MORE
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12. T cells in chronic obstructive pulmonary disease
Abstract : Background: Tobacco smoking is the main cause of chronic obstructive pulmonary disease, COPD, but the mechanisms by which cigarette smoke induces COPD are still elusive. T lymphocytes have been implicated in the pathogenesis of the disease, but their role in the airway inflammation in COPD is not fully understood. READ MORE
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13. Human intestinal T lymphocytes : a comparative analysis of phenotype and function in normal and inflamed mucosa
Abstract : The epithelial lining of the gut must allow immediate contact with beneficial components as nutrients and normal microflora. At the same time it runs the constant risk of attack from pathogenic microbes and noxious agents. READ MORE
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14. Infection induced chronic inflammation and it's association with prostate cancer initiation and progression
Abstract : An association between cancer development and inflammation has long been suggested. Approximately 20% of all human cancers in adults are assumed to result from chronic inflammation. The aim of this thesis was to investigate if infection-induced chronic inflammation plays a role in prostate carcinogenesis. READ MORE
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15. Lung-resident, M2e-specific CD4 T cells critically protect during influenza infection
Abstract : Memory CD4+ T cells are a critical component of the adaptive immune response to fight infection. However, current vaccines against influenza only focus on the other arm of adaptive immunity—triggering B cells to produce antibodies. READ MORE