Search for dissertations about: "cytotoxic T cells"

Showing result 16 - 20 of 268 swedish dissertations containing the words cytotoxic T cells.

  2. 16. Peripheral immunity in patients with autoimmune endocrine diseases and the influence of physiological adaptions during pregnancy

    Author : Louise Magnusson; Per-Ola Carlsson; Rosaura Casas; Ola Winqvist; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 diabetes; Hashimoto´s thyroiditis; Graves´ disease; autoimmune Addison´s disease; antigen-presenting cells; B cells; non-classical monocytes; NK cells; memory CD8 T cells; CDCP1; SLAMF1; inflammation; lymphocyte activation; pregnancy; β-cell function; C-peptide; plasma proteome; prolactin; prokineticin-1; glucagon; oral glucose tolerance test; mass cytometry; proximity extension assay; Medicinsk vetenskap; Medical Science; Klinisk immunologi; Clinical Immunology; Endocrinology and Diabetology; Endokrinologi och Diabetologi; Obstetrik och gynekologi; Obstetrics and Gynaecology;

    Abstract : Type 1 diabetes (T1D), Hashimoto’s thyroiditis (HT), Graves’ disease (GD), and autoimmune Addison’s disease (AD) appear to share immunogenetic mechanisms. This idea is not novel, as “autoimmune tautology” is an established concept. READ MORE

  4. 17. Immune cells in pregnant uterine mucosa : functional properties, cellular composition and tissue organization

    Author : Lucia Mincheva-Nilsson; Sten Hammarström; Rolf Kiessling; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; immunologically privileged site; TCR γδ cells; CD56 cells; large granular lymphocytes; immunosuppression; cytokine; interleukin; lymphoid cell cluster; intraepithelial lymphocytes; glandular epithelium; immuno electron microscopy; pregnancy; decidua; lactoferrin; lactoferrin receptor; colostrum;

    Abstract : The pregnant uterus mucosa - decidua - is an "immunologically privileged" site. A semiallogeneic embryo is allowed to survive, develop, and grow while the same tissue implanted outside the uterus will be rejected. The decidua basalis, which participates in the placenta formation, is a tissue rich in lymphoid cells. READ MORE

  5. 18. Recognition requirements and regulatory events directing T cell responses

    Author : Martin Gullberg; Eva-Lotta Larsson; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; T cell growth factor production; Lyt-2-positive T suppressor cell; Lyt-2-positive cytotoxic T lymphocytes; activation requirements of T lymphocytes; blocking of T cell functions;

    Abstract : The present study has considered cellular and molecular requirements in T cell responses. The central role of T cell growth factors (TCGF) in T cell responses prompted us to study the regulatory events directing TCGF production in lectin stimulated cultures. READ MORE

  6. 19. Thymic Stroma and T Cell Development. Impacts of Retinoic Acid Signaling

    Author : Kerstin Wendland; Slemhinnans immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Thymus; Thymic epithelial cells; Retinoic acid; T cell development; Stromal Cells;

    Abstract : The development of functionally competent, self-tolerant T cells in the thymus is an essential prerequisite for the formation of adaptive immune responses against foreign pathogens. Thymic epithelial cells (TECs) form specialized stromal microenvironments in the cortex (cTEC) and medulla (mTEC) of the thymus that support all stages of T cell development, from the entry of thymocyte progenitors to the exit of mature naive T cells. READ MORE

  7. 20. T-cells in COPD to help or harm? A study of T-cells in COPD patients and related aspects of T-cell function in vitro

    Author : Pernilla Glader; allergologi och palliativ medicin Lungmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Andningsorganen; Respiratory system; Immunologi; serologi; T-cell; inflammation; mucosal immunology; transplantation; serology; Immunology; lymphocyte; chronic obstructive pulmonary disease;

    Abstract : Chronic obstructive pulmonary disease, COPD, is manifested by chronic airflow limitation due to inflammation and tissue destruction in the lungs. COPD is caused primarily by smoking and with increasing cigarette consumption in the world, the prevalence for COPD will most probably increase in the future. READ MORE