Search for dissertations about: "dendritic potentials"

Showing result 1 - 5 of 10 swedish dissertations containing the words dendritic potentials.

  2. 1. A-type Potassium Channels in Dendritic Integration : Role in Epileptogenesis

    Author : Jenny Tigerholm; Erik Fransén; Fredrik Elinder; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; epileptogenesis; fast ripples; synchronicity; dendritic potentials; transient A–type potassium current; KV 4.2; Computer and systems science; Data- och systemvetenskap;

    Abstract : During cognitive tasks, synchronicity of neural activity varies and is correlated with performance. However, there may be an upper limit to normal synchronised activity – specifically, epileptogenic activity is characterized byexcess spiking at high synchronicity. READ MORE

  4. 2. Mechanisms of excitability in the central and peripheral nervous systems : Implications for epilepsy and chronic pain

    Author : Jenny Tigerholm; Erik Fransén; Dieter Jaeger; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Dendritic excitability; synchronized synaptic input; multicompartment model; epilepsy; axonal excitability; silent C–fibres; Hodgkin–Huxley dynamics; conduction velocity; KA;

    Abstract : The work in this thesis concerns mechanisms of excitability of neurons. Specifically, it deals with how neurons respond to input, and how their response is controlled by ion channels and other active components of the neuron. READ MORE

  5. 3. Non-linear synaptic integration on dendrites of striatal medium-spiny neuron : a computational study

    Author : Kai Du; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Striatum is the main input nucleus of basal ganglia. Medium-spiny neurons (MSNs), the principal neurons of the striatum, receive convergent excitatory inputs from cortex and thalamus, thus “gate” the information flow to the basal ganglia. READ MORE

  6. 4. Extra- and intracellular electronic conductance of signals and its significance for synaptic plasticity

    Author : Isaac Shemer; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Electrical signals play a pivotal role in the normal function of most if not all organisms. Understanding the electrophysiological principles that govern electrical signaling is essential for insights into normal- and pathological processes in cell biology. READ MORE

  7. 5. Ion channels and intrinsic membrane properties of locomotor network neurons in the lamprey spinal cord

    Author : Di Wang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Ion channels; calcium activated non-selective cation current ICAN ; L-type LVA calcium channels Cav 1.3 ; calcium channels; calcium imaging; NMDA; postinhibitory rebound PIR ; lamprey; central pattern generator CPG ; locomotion;

    Abstract : NMDA-receptor dependent membrane potential oscillations and postinhibitory rebound are examples of intrinsic membrane properties of many neurons of rhythm-generating networks, and are considered to play major roles in the operation of the spinal locomotor network of the lamprey vertebrate model. A significant feature of many lamprey spinal cord neurons is their ability to generate pacemaker-like membrane potential oscillations in the presence of the glutamate agonist NMDA. READ MORE