Search for dissertations about: "design of experiments"

Showing result 21 - 25 of 1388 swedish dissertations containing the words design of experiments.

  1. 21. Multivariate design of molecular docking experiments : An investigation of protein-ligand interactions

    Author : David Andersson; Anna Linusson Jonsson; Gabriele Cruciani; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Molecular docking; chemometrics; multivariate analysis; principal component analysis; PCA; design of experiments; DoE; partial least-square projections to latent structures; PLS; scoring functions; ligand-binding cavity; major histocompatibility complex; MHC; glycopeptide; T-cell.; Pharmaceutical chemistry; Läkemedelskemi; datorlingvistik; computational linguistics;

    Abstract : To be able to make informed descicions regarding the research of new drug molecules (ligands), it is crucial to have access to information regarding the chemical interaction between the drug and its biological target (protein). Computer-based methods have a given role in drug research today and, by using methods such as molecular docking, it is possible to investigate the way in which ligands and proteins interact. READ MORE

  2. 22. Around Over Between Up... : Spatial properties as variables in textile design

    Author : Tonje Kristensen Johnstone; Lars Hallnäs; Anne Louise Bang; Högskolan i Borås; []
    Keywords : HUMANIORA; HUMANITIES; Textiles and Fashion Design ; Textil och mode konstnärlig ;

    Abstract : With a starting point in defining space through materials, colours, planes, and surfaces, the aim of the work presented in this thesis was to explore and introduce spatial concepts as design variables in textile design. Another aim was to explore surface patterns in terms of their possible functions as spatial definers, and to make spatial properties (which here take the form of implicit knowledge) explicit in design processes in order to increase awareness of spatial concerns in surface pattern design. READ MORE

  3. 23. Changeability as a quality in textile design

    Author : Riikka Talman; Högskolan i Borås; []
    Keywords : HUMANIORA; HUMANITIES; Textiles and Fashion Design ; Textil och mode konstnärlig ;

    Abstract : The tendency to wear out and change is inherent in most materials, but – aside from a few exceptions – has been considered to be undesirable by both the industry and consumers. The work presented in this licentiate thesis suggests that, due to change in some form being an inherent property of textiles, it may be viable to look for alternative ways of designing and perceiving textiles that accept change as one of their qualities. READ MORE

  4. 24. Robust inference of gene regulatory networks : System properties, variable selection, subnetworks, and design of experiments

    Author : Torbjörn E. M. Nordling; Elling W Jacobsen; Rolf Findeisen; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; network inference; reverse engineering; variable selection; model selection; feature selection; subset selection; system identification; system theory; network theory; subnetworks; design of experiments; perturbation experiments; gene regulatory networks; biological networks;

    Abstract : In this thesis, inference of biological networks from in vivo data generated by perturbation experiments is considered, i.e. deduction of causal interactions that exist among the observed variables. Knowledge of such regulatory influences is essential in biology. READ MORE

  5. 25. Knitted architecture and wind: Designing loosely fitted architectural textiles for interaction with wind

    Author : Erica Hörteborn; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; HUMANIORA; HUMANITIES; HUMANIORA; HUMANITIES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Textile architecture; Knitted textiles; Wind performance; Wind; Research by design; Kinetic architecture; Geometric expression; Wind simulation; Architectural design;

    Abstract : Utilising the textile’s ability to adapt to external forces such as the wind could lead to the creation of new design expressions and functional features within architecture. Prompted by architectural potentials of textiles deliberately designed to move and flex, this thesis aims to explore and demonstrate how such knitted textiles could contribute to enriched aesthetic expression and improved performance of architectural elements placed in windy environments. READ MORE