Search for dissertations about: "developmental expression"
Showing result 1 - 5 of 462 swedish dissertations containing the words developmental expression.
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1. Developmental exposure to mixtures of environmental pollutants : Studies on metabolism, developmental processes, and reproductive organs in zebrafish and chicken embryos
Abstract : Humans and wildlife are continuously exposed to mixtures of environmental pollutants. Mixture toxicity can be challenging to predict due to interactions between chemicals and thus whole-mixture approaches are crucial in toxicology. READ MORE
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2. Sexually Dimorphic Gene Expression in the Mammalian Brain
Abstract : In recent times, major advances have been made towards understanding sexual dimorphism in the brain on a molecular basis. This thesis summarises my modest contributions to these endeavours. Sexual dimorphisms are manifested throughout the spectrum of biological complexity, and can be studied by numerous approaches. READ MORE
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3. Gene expression and its physiological control in disease and development : Studies on the human PDGF-B gene and tumour hypoxia
Abstract : Strict control of gene expression is essential during development and in response to physiological stimuli. This thesis describes the functional characterisation of the gene regulatory mechanisms controlling the expression of the potent human growth factor Platelet Derived Growth Factor B gene, in a cell type specific context and in response to low oxygen tension. READ MORE
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4. Functions of Transcriptional Co-regulators in Drosophila development
Abstract : During Drosophila development, regulation of gene expression through interplay between transcriptional activators and repressors is generating complex patterns of gene expression that leads to cell differentiation. For proper control of transcription, transcription factors bind to DNA at control regions, so called Cis Regulatory Modules (CRM). READ MORE
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5. Grainy head target genes in epithelial morphogenesis and wound healing
Abstract : grainy head (grh) genes encode a family of transcription factors conserved from fly to human. Drosophila grh is the founding member of this gene family and has multiple functions, including tracheal tube size control, epidermal barrier formation and reconstruction after wounding. READ MORE