Search for dissertations about: "developmental origins of health and disease"
Showing result 1 - 5 of 9 swedish dissertations containing the words developmental origins of health and disease.
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1. Bioinformatic and Biostatistic Analysis of Epigenetic Data from Humans and Mice in the Context of Obesity and its Complications
Abstract : Worldwide obesity has more than doubled since 1980 and at least 2.8 million people die each year as a result of being overweight or obese. An elevated body weight is the result of the interplay between susceptibility gene variants and an obesogenic environment, and recent evidence shows that epigenetic processes are likely involved. READ MORE
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2. Early life influences on adult organ function, health and disease, including data from Swedish population-based cohorts
Abstract : Prenatal insults or adverse events during the in-utero period may lead to suboptimal function of adult organs because of the impairment of critical organ development and growth, as linked to lower birth weight. This may ultimately predispose the individual to the later onset of some diseases in adulthood, a process known as Developmental Origins of Health and Disease (DOHaD). READ MORE
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3. Who is Who in the Adipose Organ : A look at the Heterogeneity of Adipocyte Biology
Abstract : The increasing prevalence of obesity and related health complications, such as type 2 diabetes, cardiovascular disease and cancer, demands thorough investigation of the underlying processes. One of the key tissues investigated in this context is adipose tissue. READ MORE
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4. Maternal stress and allergic disease in offspring
Abstract : The theory of developmental origins of health and disease (DOHaD), hypothesize that diseases like allergy is formed in-utero and early life by interaction between adverse environmental factors and genetic predisposition. The study population in this thesis consists of mother-child pairs from the PreventADALL cohort. READ MORE
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5. Early life determinants of socioeconomic and health inequalities : life course studies within and across generations
Abstract : The role of the early life social and maternal environments in the production of health inequalities was widely documented in the past few decades but the underlying mechanisms were often subject to suboptimal analytic practices. The developmental origins of health and disease (DOHaD) paradigm came with a promise to better document the early life programming of adult diseases, with an emphasis on the postnatal modifiers of prenatal influences. READ MORE
