Search for dissertations about: "dhps"

Showing result 1 - 5 of 8 swedish dissertations containing the word dhps.

2. 1. Sulphonamide Resistance in Neisseria meningitidis and Commensal Neisseria Species

   Author : Yvonne Qvarnström; Göte Swedberg; Dan Andersson; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; sulphonamide resistance; Neisseria; natural transformation; adaptive evolution; substrate channelling; Mikrobiologi; Microbiology; immunology; infectious diseases; Mikrobiologi; immunologi; infektionssjukdomar;

   Abstract : Extensive use of the sulphonamide drugs against the bacterium Neisseria meningitidis has resulted in drug resistance development. Sulphonamide resistance in N. meningitidis is caused by alterations in the chromosomal folP gene, coding for DHPS (dihydropteroate synthase). READ MORE

4. 2. Genetic and antigenic diversity in Pneumocystis jirovecii

   Author : Jessica Beser; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Pneumocystis jirovecii is a human specific, atypical fungus with a worldwide distribution that causes disease in immunocompromised individuals. The fungus proliferates in the lungs where it binds to epithelial alveolar cells, provoking severe pneumonia, denoted pneumocystis pneumonia (PCP). READ MORE

5. 3. Microbial Responses to Antibiotics – Stability of Resistance and Extended Potential of Targeting the Folate Synthesis

   Author : Maria Jönsson; Göte Swedberg; Steven Meshnick; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; sulfonamide resistance; macrolide; commensal flora; substrate channeling; folate synthesis; Molekylärbiologi; Molecular biology; Molekylärbiologi;

   Abstract : Resistance to antimicrobials is an increasing problem in the world of today, and develops faster than man can counter. It is therefore of importance to study metabolic pathways in order to develop new antibiotics, but also to understand how resistance spreads and stabilizes in microbial populations. READ MORE

6. 4. Biochemical Control Aspects in Lignin Polymerization

   Author : Anders Holmgren; Gunnar Henriksson; Liming Zhang; Jussi Sipilä; KTH; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Lignin polymerization; DHP; Ascorbic Acid; NADH; template polymerization; melanin; Chemistry; Kemi;

   Abstract : Lignins are produced by all vascular plants and they represent one of the most abundant groups of biopolymers in nature. Lignin chemistry research, which has been of great importance for the progress of pulping technologies, has been plagued by the difficulties of its isolation and characterization. READ MORE

7. 5. Factors Influencing Evolution to Antimalarial Drug Resistance in Plasmodium falciparum in Sudan and The Gambia

   Author : Amany Kheir; Göte Swedberg; Susanne Kerje; Hamza Babiker; Staffan Svärd; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cross-mating; fitness; microsatellite haplotypes; mosquito infectivity; Infectious diseases; Infektionssjukdomar; Molekylär genetik; Molecular Genetics;

   Abstract : Drug resistance is a major obstacle to management and control of malaria and currently progressing at a rapid rate across Africa. This thesis has examined factors influencing evolution of resistant P. falciparum at two sites in Africa, including parasite migration, cross mating and fitness cost of resistance. READ MORE