Search for dissertations about: "diabetes, children and adolescents"

Showing result 1 - 5 of 45 swedish dissertations containing the words diabetes, children and adolescents.

  1. 1. Type 1 diabetes in children with non-Swedish background : epidemiology and clinical outcome

    Author : Ulf Söderström; Jan Åman; Ulf Samuelsson; Anders Hjern; Jannet Svensson; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 diabetes; HbA1c; children; adolescents; ethnicity; epidemiology; immigration; adoption; socio-demographic; registers; Medicine; Medicin;

    Abstract : Sweden holds third place of diabetes incidence in young people after Finland and Sardinia. One fifth of the population is nowadays of foreign descent. We have a substantial number of immigrants from countries where the risk for T1D is considerably lower. READ MORE

  2. 2. Aspects of chronic autoimmune thyroiditis in children and adolescents

    Author : Johan Svensson; Pediatrisk endokrinologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adolescents; thyroid autoantibodies; enterovirus infection; thyroid ultrasonography; reference standard; goiter; chronic autoimmune thyroiditis; levothyroxine treatment; Medicin människa och djur ; Medicine human and vertebrates ; children;

    Abstract : The aims of this thesis were to 1) compare different methods for detection of antibodies against thyroglobulin (TgAb) and thyroid peroxidase (TPOAb), particulary in children with chronic autoimmune thyroditis (AIT), 2) investigate if maternal enterovirus infection is a risk factor for development of AIT in offspring, 3) ascertain the prevalence of thyroid autoantibodies in cord blood sera from children who later developed AIT, 4) develop a new reference standard for interpretation of normative thyroid volumes in Swedish children, and 5) evaluate the effect of Levothyroxine (L-thyroxine) treatment on thyroid size in children and adolescents with AIT. We found that 1) Methods based on radioimmunoassay (RIA) were more efficient in detecting both TgAb and TPOAb in children with AIT than methods based on agglutination. READ MORE

  3. 3. Differences in glycemic control in type 1 diabetes children and adolescents : in a national and international perspective and the effect on microvascular complications in young adults

    Author : Johan Anderzén; Ulf Samuelsson; Lena Hanberger; Karin Åkesson; Carina Sparud Lundin; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : This thesis focuses on glycemic control measured as HbA1c in type 1 diabetes (T1D) patients during childhood and especially during adolescence, both in a Swedish and an international context, and relates the glycemic control to the risk of complications in young adults.  In studies I and II, the Swedish Pediatric Diabetes Quality Register (SWEDIABKIDS) and the Swedish National Diabetes Register (NDR) were used. READ MORE

  4. 4. Impaired Glucose Tolerance in Childhood Obesity : Contribution of Glucagon, GLP-1 and Inflammation

    Author : Hannes Manell; Peter Bergsten; Anders Forslund; Jens Juul Holst; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Childhood obesity; impaired glucose tolerance; type 2 diabetes; glucagon; glucagon-like peptide-1; dipeptidyl peptidase-4; inflammation; free fatty acids; insulin; visceral adiposity; Medicinsk vetenskap; Medical Science;

    Abstract : In the wake of increased obesity prevalence, impaired glucose tolerance (IGT) and type 2 diabetes (T2D) in childhood and adolescence is increasingly common. Given the negative impacts these conditions have on health over time, understanding the pathophysiology in those affected early in life is important. READ MORE

  5. 5. Perinatal risk factors for type 1 diabetes in children and adolescents

    Author : Nina Lindell; Ulf Samuelsson; Ann Josefsson; Annelie Carlsson; Mikael Knip; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Background Type 1 diabetes (T1D) is an autoimmune disease characterized by progressive loss of the insulin producing pancreatic β-cells. The disease process starts years before the clinical diagnosis. The cause of T1D is unknown, but it is believed to be a combination of genetic and environmental factors. READ MORE