Search for dissertations about: "diabetes cure"

Showing result 1 - 5 of 30 swedish dissertations containing the words diabetes cure.

  2. 1. Immunopathology of the Pancreas in Type 1 Diabetes

    Author : Anna Wiberg; Olle Korsgren; Oskar Skog; Åke Lernmark; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 diabetes; glucagon; T cells; autoantibodies; glucose transporters; islets of Langerhans; pancreas; Klinisk immunologi; Clinical Immunology;

    Abstract : Type 1 diabetes (T1D) results from a loss of functional insulin-producing pancreatic beta cells. The etiology of T1D is poorly understood, but the detection of infiltrating inflammatory cells in the pancreas and circulating autoantibodies has led to the common notion that an autoimmune process plays a central role in the pathogenesis of the disease. READ MORE

  4. 2. The Role of Maf Transcription Factors in Islet Inflammation and Βeta Cell Function

    Author : Tania Singh; Stamcellscentrum (SCC); []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Diabetes; T cells; pancreas; resident lymphocytes; autoimmunity; Insulin secretion; pancreas development; Type 1 and Type 2 diabetes; inflammation and leukocyte; Cytokines: immunology; Transcription Factor MAFs; Interferons;

    Abstract : Endocrine disorders that lead to a state of chronic high blood glucose levels are collectively referred to as diabetes. This metabolic disease is mainly categorized into type 1 (T1D) and type 2 diabetes (T2D). These diabetic forms originate from distinct triggering environmental, genetic, and altered mechanisms. READ MORE

  5. 3. Properties of Endothelium and its Importance in Endogenous and Transplanted Islets of Langerhans

    Author : Åsa Johansson; Per-Ola Carlsson; JanOve Sehlin; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; islet transplantation; endothelial cells; engraftment; beta cells; Diabetology; Diabetologi; Medical Cell Biology; medicinsk cellbiologi;

    Abstract : Transplantation of insulin producing cells is currently the only cure for type 1 diabetes. However, even though the Edmonton protocol markedly increased the success rate of pancreatic islet transplantation, the long term insulin independence is still very poor. An adequate engraftment is critical for islet graft survival and function. READ MORE

  6. 4. Genetic Alterations and Molecular Signatures in Aldosterone Producing Adenomas

    Author : Tobias Åkerström; Peyman Björklund; Tracy Ann Williams; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Aldosterone; aldosterone producing adenoma; KCNJ5; ATP1A1; ATP2B3; CACNA1D; CTNNB1;

    Abstract : Primary Aldosteronism (PA) is caused by autonomous overproduction of aldosterone. Aldosterone is necessary for fluid and ion homeostasis. Aberrant overproduction leads to hypertension and cardiovascular damage. READ MORE

  7. 5. Microcirculation in native and transplanted rodent pancreatic islets with special reference to the influence of diabetes mellitus

    Author : Per-Ola Carlsson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; Diabetes; pancreatic islets; islet microcirculation; microspheres; micropuncture technique; islet blood flow; islet capillary pressure; oxygen tension; transplanted islets; Cellbiologi; Cell biology; Cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

    Abstract : The aim of the present work was to characterize the islet microcirculation in animal models of type 1 and type 2 diabetes, as well as in islets transplanted to diabetic or normoglycemic recipients. For this purpose, a microsphere technique was evaluated and applied for measurements of islet blood flow in mice. READ MORE