Search for dissertations about: "diabetes type 1 and c3"

Showing result 1 - 5 of 7 swedish dissertations containing the words diabetes type 1 and c3.

  2. 1. Aspects on wall properties of the brachial artery in man : with special reference to SLE and insulin-dependent diabetes mellitus

    Author : Niclas Bjarnegård; Toste Länne; Reinhard Volkmann; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Arterial wall; atherosclerotic; brachial artery BA ; type 1 diabetes; ulse wave velocity PWV ; pulse wave analysis PWA ; intima-media thickness IMT ; nitrate mediated dilatation NMD ; Diabetology; Diabetologi;

    Abstract : The mechanical properties of the arterial wall are of great importance for blood pressure regulation and cardiac load. With increasing age, large arteries are affected by increased wall stiffness. READ MORE

  4. 2. Innate immunity in diabetes mellitus. Complement components C4BP and C3 promote survival of β cells under metabolic challenges

    Author : Klaudia Kulak; Malmö Proteinkemi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Complement System; Inflammasome; Islet Amyloid Polypeptide; Complement C3; C4b-binding protein C4BP ; Interleukin 1β; Autophagy-Related Protein 16 like 1; Diabetes mellitus; type 2;

    Abstract : The Complement system is a main effector mechanism of the innate immune system, acting to enhance clearance of pathogens, but also aids removal of biological debris from the body, including immunocomplexes, apoptotic/necrotic cells and protein aggregates. Complement regulators serve to prevent excessive inflammation and their interaction with the same materials targeted by the complement system results in ‘silent’ cleaning of wastes. READ MORE

  5. 3. Modern roles for an ancient system. Intracellular Complement in the regulation of β cell function

    Author : Ewelina Golec; Malmö Proteinkemi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Complement system; Diabetes mellitus; Insulin secretion; CD59; C3; Isoforms; SNARE proteins;

    Abstract : Type 2 diabetes (T2D) is characterised by defective insulin exocytosis from the pancreatic β cells, accompanied by insulin resistance. Reduced β cells mass is often seen in T2D individuals, caused by enhanced β cells apoptosis. It is now understood that several components drive β cells dysfunction and apoptosis. READ MORE

  6. 4. Periodontitis, carotid calcifications and future cardiovascular diseases in older individuals

    Author : Viveca Wallin Bengtsson; Stefan Renvert; Malmö universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parodontit;

    Abstract : Background. Periodontitis is a chronic inflammatory disease with a microbiological etiology affecting the supporting tissues of the tooth. The disease affects approximately 50% of the adult population. The prevalence of periodontitis increases with age. READ MORE

  7. 5. Human adipose tissue. Genes predominantly expressed in the visceral depot and in hypertrophic adipocytes

    Author : Jenny Palming; Göteborgs universitet; []
    Keywords : obesity; type 2 diabetes; adipose tissue depots; complement system; plasma cell; Fc receptor; serum amyloid A; NAD P H:quinone oxidoreductase 1; DNA microarray;

    Abstract : The obesity prevalence is increasing worldwide and obesity is closely linked to type 2 diabetes and cardiovascular disease. Both visceral fat accumulation and enlarged adipocyte size are risk factors for obesity related metabolic disorders. READ MORE