Search for dissertations about: "dicarbonyl"

Showing result 1 - 5 of 7 swedish dissertations containing the word dicarbonyl.

  2. 1. Engineered Yeast as Biocatalyst for Stereoselective reductions of Dicarbonyl Compounds

    Author : Ted Johanson; Teknisk mikrobiologi; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; chiral; screening; process optimisation; metabolic engineering; dicarbonyl; biocatalysis; yeast; bioreduction; Biotechnology; Bioteknik;

    Abstract : Chiral building blocks are needed in the chemical and pharmaceutical industries for the production of fine chemicals and pharmaceuticals. The utilisation of microorganisms and enzymes to perform stereoselective reductions of carbonyl compounds is an efficient and widely applied method for the generation of chiral molecules. READ MORE

  4. 2. Selective Transformations of Allylic Compounds and Enol Derivatives : Synthesis of Fluorinated and Nitrogenated Scaffolds

    Author : Víctor García-Vázquez; Belén Martín‐Matute; Mario Waser; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Fluorinated compounds; Base catalysis; Ion-Pair; Isomerization; Pd catalysis; Method development; Hypervalent iodine III ; Organic Chemistry; organisk kemi;

    Abstract : In this thesis, new synthetic methods to give access to molecules having fluorinated scaffolds and other polar functional groups have been developed. The methods give access to highly valuable organic compounds that may serve as building blocks in the synthesis of functionalized drug candidates. READ MORE

  5. 3. Exploring Conjugate Addition Activity in Pseudozyma antarctica Lipase B

    Author : Maria Svedendahl; Per Berglund; Olof Ramström; Amelie Eriksson Karlström; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Candida antarctica lipase B · conjugate addition · enzyme catalysis · enzyme catalytic promiscuity · molecular modeling; Biochemistry; Biokemi;

    Abstract : Multifunctional enzymes have alternative functions or activities, known as “moonlighting” or “promiscuous”, which are often hidden behind a native enzyme activity and therefore only visible under special environmental conditions. In this thesis, the active-site of Pseudozyma (formerly Candida) antarctica lipase B was explored for a promiscuous conjugate addition activity. READ MORE

  6. 4. Probing the effects of photodegradation of acceptor materials in polymer solar cells: bulk, surface, and molecular level

    Author : Vanja Blazinic; Ellen Moons; Leif Ericsson; Thomas Wågberg; Karlstads universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; photovoltaics; polymer solar cell; conjugated polymers; fullerene; photo-oxidation; spectroscopy; Physics; Fysik;

    Abstract : Polymer solar cells (PSC) have reached record power conversion efficiencies of over 15%. The operational lifetime of PSCs, however, has to increase for their use in large area outdoor applications. READ MORE

  7. 5. Substrate specificities and functional properties of human short-chain dehydrogenases / reductases

    Author : Sheikh Naeem Shafqat; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Short-chain dehydrogenases/reductases (SDRs) constitute a universal superfamily of functionally heterogeneous proteins and participate in the metabolism of steroids, prostaglandins, retinoids, aliphatic alcohols, and xenobiotics. So far, more than 3000 members including species variants and over 60 human SDR genes are deposited in databases. READ MORE