Search for dissertations about: "differential RNA expression."

Showing result 1 - 5 of 76 swedish dissertations containing the words differential RNA expression..

2. 1. Genome-wide Characterization of RNA Expression and Processing

   Author : Ammar Zaghlool; Lars Feuk; Rickard Sandberg; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; RNA sequencing; RNA splicing; RNA processing; Gene expression; Molekylär genetik; Molecular Genetics;

   Abstract : The production of fully mature protein-coding transcripts is an intricate process that involves numerous regulation steps. The complexity of these steps provides the means for multilayered control of gene expression. READ MORE

4. 2. Analysis of RNA and DNA sequencing data : Improved bioinformatics applications

   Author : Benjamín Sigurgeirsson; Joakim Lundeberg; Simon Anders; KTH; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; RNA sequencing; exome sequencing; bioinformatics; gene expression; differential expression; variant calling; Bioteknologi; Biotechnology;

   Abstract : Massively parallel sequencing has rapidly revolutionized DNA and RNA research. Sample preparations are steadfastly advancing, sequencing costs have plummeted and throughput is ever growing. This progress has resulted in exponential growth in data generation with a corresponding demand for bioinformatic solutions. READ MORE

5. 3. Endogenous Retroviral RNA Expression in Humans

   Author : Lijuan Hu; Jonas Blomberg; Göran Friman; Francois Mallet; Uppsala universitet; []
   Keywords : Microbiology; Human endogenous retrovirus HERV ; HERVE; HERVW; betaretrovirus; gammaretrovirus; RNA expression; real time PCR; endometrium; endometriosis; brain tissue; reproductive tissue; ovarian cancer; ovary; neuroblastoma cell line; Mikrobiologi;

   Abstract : Human endogenous retroviruses (HERVs) constitute about 8% of the human genome. There are around 4000 pol-containing retroviral integrations in the human genome, which makes it impractical to measure each of them separately. READ MORE

6. 4. Chromosome-specific adaptations of RNA stability and the roles of the roX RNAs in dosage compensation

   Author : Marie-Line Faucillion; Jan Larsson; Jean-Yves Roignant; Umeå universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Drosophila melanogaster; dosage compensation; buffering; RNA stability; RNA decay; RNA half-life; RNA-seq; genome-wide; sex chromosomes; evolution; roX1; roX2; POF; MSL; molekylärbiologi; Molecular Biology;

   Abstract : Sex chromosomes evolved from an ancient pair of autosomes and the Y chromosome lost most of its genetic information in the process. This created two kinds of genomic imbalances: the first one between males (XY) and females (XX) and the second one between the sex chromosomes and the autosomes (X:AA). READ MORE

7. 5. Differential RNA expression in benign and malignant adrenocortical tumours

   Author : David Velázquez-Fernández; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Adrenocortical; microarray; mRNA; cancer; tumors; cDNA; expression profiles; aldosterone; cortisol; endocrine; adenomas; carcinomas; IGF2; ALDH1A1.;

   Abstract : Adrenocortical cancer is a rare but very aggressive endocrine tumor, with a yearly incidence of 0.5 to 2 cases per million inhabitants, accounting for 0.2% of all cancer related deaths. READ MORE