Search for dissertations about: "digital microfluidic"

Showing result 1 - 5 of 34 swedish dissertations containing the words digital microfluidic.

  1. 1. Single Molecule Detection : Microfluidic Automation and Digital Quantification

    Author : Malte Kühnemund; Mats Nilsson; Ulf Landegren; Sten Linnarsson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; single molecule; digital; rolling circle amplification; magnetic particle; padlock probe; microfluidics; resistive pulse sensing; lab on chip; mobile phone microscopy; enrichment; sequencing;

    Abstract : Much of recent progress in medical research and diagnostics has been enabled through the advances in molecular analysis technologies, which now permit the detection and analysis of single molecules with high sensitivity and specificity. Assay sensitivity is fundamentally limited by the efficiency of the detection method used for read-out. READ MORE

  2. 2. Heterogeneous Technologies for Microfluidic Systems

    Author : Gunjana Sharma; Klas Hjort; Sami Franssila; Uppsala universitet; []
    Keywords : actuator; biosensor; fluidic circuit board; heterogeneous technology; ion track; microfluidic; pump; stainless steel; super-hydrophobic; valve; Viton; TECHNOLOGY; TEKNIKVETENSKAP; Teknisk fysik med inriktning mot mikrosystemteknik; Engineering Science with specialization in Microsystems Technology;

    Abstract : In this thesis, conventional and unconventional technologies have been studied and combined in order to make heterogeneous microfluidics with potential advantages, especially in biological applications. Many conventional materials, like silicon, glass, thermoplastic polymers, polyimide and polydimethylsiloxane (PDMS) have been combined in building heterogeneous microfluidic devices or demonstrators. READ MORE

  3. 3. Digital Electrical DNA Sensing

    Author : Maoxiang Guo; Wouter van der Wijngaart; Fredrik Westerlund; KTH; []
    Keywords : DNA detection; thiol-ene-epoxy; rolling circle amplification; digital measurement; DNA stretching; microwell-array; gold nanowires; electrical measurement; specificity; limit of detection; liquid storage; disease diagnosis; lab-on-a-chip; point-of-care.;

    Abstract : Molecule detection is a workhorse in life sciences and medicine, for example in cancer diagnosis and virus and bacterial detection. DNA analysis can provide vital information about the state of a host organism and its medical and health condition. READ MORE

  4. 4. Microfluidic Devices for Manipulation and Detection of Beads and Biomolecules

    Author : Mats Jönsson; Ulf Lindberg; Bertil Hök; Johan Nilsson; Uppsala universitet; []
    Keywords : Engineering physics; sensor; micro; dielectrophoresis; impedance; electrode; beads; cell; flow; bacteria; microfabrication; biosensor; electrocapture; microfluidic; planar; Lab on chip; µTAS; micro total analysis system; QCM; dispersion; field-flow fractionation; ITO; design; fabrication; Teknisk fysik;

    Abstract : This thesis summarises work towards a Lab-on-Chip (LOC). The request for faster and more efficient chemical and biological analysis is the motivation behind the development of the LOC-concept. Microfluidic devices tend to become increasingly complex in order to include, e.g. READ MORE

  5. 5. Paraffin Actuators in Microfluidic Systems

    Author : Marcus Lehto; Klas Hjort; Peter Woias; Uppsala universitet; []
    Keywords : Engineering physics; Paraffin; Actuators; Valve; Micropump; Teknisk fysik;

    Abstract : There is a need for reliable valves and pumps in microfluidics. A good microactuator is the key for low cost and high performance of these components.Paraffin wax is a promising material to be used as actuator material as is can produce large forces and large strokes. READ MORE