Search for dissertations about: "dissertation on medicinal chemistry"

Showing result 1 - 5 of 16 swedish dissertations containing the words dissertation on medicinal chemistry.

  2. 1. Aspects on optimisation of drug therapy in the elderly

    Author : Åsa ÅB Bondesson; Avdelningen för klinisk kemi och farmakologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; medication histories; medication reviews; drug-related problems; elderly; medication errors; pharmacists; drug therapy;

    Abstract : Introduction: Elderly patients often use many drugs, increasing the risk for drug-related problems. Aim: To optimise drug therapy in the elderly by identifying, resolving and preventing drug-related problems. READ MORE

  4. 2. Studies on a serine peptidase inhibitor locus on human chromosome 20 Characterization of novel genes encoding proteins with WFDC and kunitz domains

    Author : Adam Clauss; Malmö Klinisk kemi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin människa och djur ; Medicine human and vertebrates ; kunitz; Protase inhibitor; WFDC;

    Abstract : An unlimited number of proteolytic reactions are carried out by enzymes in biological systems. These enzymes are a necessity of life, but they can also be dangerous if they are not controlled. READ MORE

  5. 3. Synthesis, Function, and Inactivation of Blood Coagulation Factor V

    Author : Kristoffer Sørensen; Malmö Klinisk kemi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; activated protein C; heparin; calcium binding; R2 haplotype; Blood Coagulation; Factor V; Clinical chemistry; Klinisk kemi;

    Abstract : Blood coagulation factor V (FV) is a 330 kDa plasma glycoprotein. Activated FV (FVa) is a non-enzymatic cofactor to activated Factor X in the activation of prothrombin that occurs during coagulation. READ MORE

  6. 4. Aspects on optimisation of High Dose Methotrexate treatment in children with Acute Lymphoblastic Leukaemia

    Author : Peter Jönsson; Avdelningen för klinisk kemi och farmakologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; high dose methotrexate; exposure; dosing algorithms; renal function; cerebrospinal fluid; childhood acute lymphoblastic leukaemia; population pharmacokinetics; relapse risk;

    Abstract : Childhood Acute Lymphoblastic Leukaemia (ALL) has a unique place in the history of oncology, as it was the first cancer to be cured by drugs. It is therefore an important model upon which concepts of chemotherapy in other malignancies have been developed. Methotrexate is a major component of most contemporary childhood ALL treatment protocols. READ MORE

  7. 5. The Kallikrein-Related Peptidases hK2 and PSA with Emphasis on Genetic Variation, Secretion, and Sperm Motility

    Author : Charlotta Sävblom; Malmö Klinisk kemi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human glandular kallikrein 2; KLK3; hk2; prostate-specific antigen; PSA; sperm motility; seminal plasma; androgen receptor; SNP; CAG; KLK2;

    Abstract : Prostate-specific antigen (PSA) and human glandular kallikrein 2 (hK2) are secreted by the prostate into seminal plasma and through leakage into blood. This leakage increases rapidly in prostate disease, and PSA is used worldwide as a marker of prostate cancer. READ MORE