Search for dissertations about: "dopamine agonist"

Showing result 1 - 5 of 73 swedish dissertations containing the words dopamine agonist.

  2. 1. Dopamine D2 and D3 receptors. Studies on transduction mechanisms and on the role of a D3 gene polymorphism

    Author : Monika Hellstrand; Göteborgs universitet; []
    Keywords : dopamine; dopamine D2 receptor; dopamine D3 receptor; transduction; CHO cells; partial agonism; inverse agonism; arachidonic acid; prostaglandin E2; cAMP; haloperidol; -3-PPP; PNU-99194A; polymorphism; personality;

    Abstract : The neurotransmitter dopamine has been implicated in the pathophysiology of, e.g., Parkinson s disease and schizophrenia, and dopamine receptor-active compounds are commonly employed therapeutically in these and other disorders. READ MORE

  4. 2. Selectivity of dopamine D1 and D2 receptor agonists – A combined computational approach

    Author : Marcus Malo; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; dopamine; agonists; GPCRs; pharmacophore modeling; protein structure modeling; agonist selectivity;

    Abstract : Dopamine (DA) is an endogenous neurotransmitter acting in the central nervous system. DA plays a key role in many vital brain functions such as behavior, cognition, motor activity, learning, and reward. Dopamine receptors belong to the rhodopsin like family of G-protein coupled receptors (GPCRs). READ MORE

  5. 3. Pre-clinical investigations of a dopamine autoreceptor agonist : selective stimulators of central dopamine and serotonin receptors

    Author : Seth-Olov Thorberg; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PHARMACY; FARMACI;

    Abstract : .... READ MORE

  6. 4. The Role of Dopamine-Metabolising Enzymes in Renal Sodium Handling. An Experimental Study in vivo

    Author : Cecilia Odlind; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology and anatomy; dopamine; kidney; sodium; MAO; COMT; rat; mice; RBF; oxygen; renal; L-dopa; DOPAC; entacapone; phenelzine; dopamine receptors; Fysiologi och anatomi; Physiology and pharmacology; Fysiologi och farmakologi; Physiology; fysiologi;

    Abstract : Dopamine (DA) has been shown to act as an intrarenal natriuretic hormone and defects in the renal DA system have been associated with some forms of hypertension. How the DA activity is upregulated durin- increased sodium intake is, however, unknown. READ MORE

  7. 5. Morphological and Physiological Adaptations in Cichlid Crystalline Lenses

    Author : Marcus Schartau; Biologiska institutionen; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; SKF-38393; D1-agonist; optical properties 6-hydroxydopamine; optical measurements; organ culture; dopamine; teleost; lens circulation; Lens; SCH-23390; melatonin; multifocal optical system;

    Abstract : Vertebrate eyes share a common ancestry as well as the basic design with a pupil, a retina and a lens. The lens is essential for perceiving the details in the world around us and ensures that a sharp image of the surroundings is focused onto the photoreceptors in the retina. READ MORE