Search for dissertations about: "dopamine synthesis rate"

Showing result 1 - 5 of 13 swedish dissertations containing the words dopamine synthesis rate.

  2. 1. PET applications in schizophrenia : Functional and pharmacological dopamine studies

    Author : Ola Gefvert; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Schizophrenia; PET; dopamine synthesis rate; dopamine D2 receptor occupancy; atypical antipsychotics; quetiapine; risperidone microsphere depot; Neurovetenskap; Neurology; Neurologi; Psychiatry; psykiatri;

    Abstract : Schizophrenia is a group of disorders with a worldwide lifetime prevalence of 0.85%. Thefunctional outcome of the disorder seem stable from the first systematic outcome studies to thepresent day, and vary only with changes in diagnostic criteria. READ MORE

  4. 2. Cyanide and central nervous system : a study with focus on brain dopamine

    Author : Gudrun Cassel; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CNS; cyanide; dopaminergic system; convulsions; receptor binding; tyrosine hydroxylase; monoamine oxidase; extracellular release; inositol phosphate; GABA; GAD;

    Abstract : The brain is a major target site in acute cyanide intoxication, as indicated by several symptoms and signs. Cyanide inhibits the enzyme cytochrome oxidase. This inhibition causes impaired oxygen utilization in all cells affected, severe metabolic acidosis and inhibited production of energy. READ MORE

  5. 3. Importance of endogenous kynurenic acid in brainm catecholaminergic processes and in the pathophysiology of schizophrenia

    Author : Sophie Erhardt; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Schizophrenia; kynurenic acid; nicotine; VTA; dopamine; NMDA-receptors;

    Abstract : Kynurenic acid is a metabolite of tryptophan and the only known naturally occurring NMethylD-Aspartic acid (NMDA)-receptor antagonist (at the co-agonist glycine site) in the human brain. The aim of the present work was to investigate the physiological and pharmacological significance of endogenous kynurenic acid as well as its putative pathophysiological implications. READ MORE

  6. 4. On retinoid receptors, Nurr1 and related transcription factors in the CNS

    Author : Rolf H Zetterström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Nurr1; NGFI-B; Nor1; RAR; RXR; CRBP; CRABP; substantia nigra; basal ganglia; dopamine; orphan receptor; vitamin A; retinoic acid; transcription factor;

    Abstract : It has long been known that retinoids (vitamin A derivatives) are required for normal development and growth; in excess however metabolites such as all-trans retinoic acid are potent teratogens. Retinoids exert their effects through transcription factors known as the retinoic acid receptors (RARam -ß and -y) and retinoid X receptors (RXRa, -ß and -y). READ MORE

  7. 5. Synthesising Metal Oxide Materials and Their Composite Nanostructures for Sensing and Optoelectronic Device Applications

    Author : Kimleang Khun; Magnus Willander; Omer Nour; Christos Tsamis; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Hydrothermal method; metal oxide nanostructure; composite seed solution; wellaligned ZnO nanorods; composite structures; glucose and dopamine non-enzymatic sensors; heavy metals; supramolecular; UV photodetector sensor;

    Abstract : Research on nanomaterials has been revolutionized in the last few years because of the attractive properties they have in comparison to the bulk phase of similar materials. These properties are physical, chemical, catalytic and optical. READ MORE