Search for dissertations about: "drug delivery nanoparticles"

Showing result 1 - 5 of 61 swedish dissertations containing the words drug delivery nanoparticles.

2. 1. Nanoparticles for multifunctional drug delivery systems

   Author : Jian Qin; Mamoun Muhammed; Paavo K J Kinnunen; KTH; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; drug delivery; stimuli-sensitive; SPION; PLLA; PNIPAAm; gold; MRI; cytotoxicity; Pluronic; phase transfer; Materials chemistry; Materialkemi;

   Abstract : Multifunctional drug delivery systems incorporated with stimuli-sensitive drug release, magnetic nanoparticles and magnetic resonance (MR) T2 contrast agents is attracting increasing attention recently. In this thesis, works on polymer nanospheres response to temperature change, superparamagnetic iron oxide nanoparticles (SPION)/polymeric composite materials for MR imaging contrast agents are summarized. READ MORE

4. 2. Multifunctional Glyconanomaterials : Applications in Biorecognition and Drug Delivery

   Author : Zhou Juan; Ramström Olof; Ravin Narain; KTH; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; glyconanomaterials; cellulose nanocrystals; chitin nanocrystals; mesoporous silica nanoparticles; lectin; biorecognition; drug delivery; bacteria; cytotoxicity; perfluorophenylazide; fluorescent dye; carbohydrate ligands.;

   Abstract : This thesis consists of three parts, which revolve around the fabrication of multifunctional glyconanomaterials (cellulose nanocrystals, chitin nanocrystals, mesoporous silica nanoparticles) and the development of their applications in biorecognition and nanomedicine.Part one presents a detailed introduction to glyconanomaterials, focusing on cellulose nanocrystals, chitin nanocrystals and mesoporous silica nanoparticles, including their general preparations, properties and applications. READ MORE

5. 3. Nanoparticle-based drug delivery systems for neural interfaces - a novel approach for improved biocompatibility

   Author : Alexander Dontsios Holmkvist; Neurofysiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; Neural interfaces; brain damage injury; Minocycline; Gelatin; Nanoparticles; Drug-delivery systems; Biocompatibility; Tissue responses; immunohistochemistry IHC ; Poly D; L-lactic-co-glycolic acid PLGA ; Hydrophobic ion paring; Emulsification-solvent-diffusion method; Drug release; Microglia activation;

   Abstract : The overall purpose of this thesis was to reduce brain tissue responses around implanted microelectrodes using a pharmacological strategy. One of the main aims was to develop and evaluate drug delivery systems that allow local administration of anti-inflammatory pharmaceutics. READ MORE

6. 4. Design of Functional Polymeric Nanoparticles for Biomedical Applications

   Author : Heba Asem; Eva Malmström; Tim Bowden; KTH; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biodegradable polymers; SPION; PISA; RAFT; nanoparticles; drug delivery; cytotoxicity; MRI; in vivo fluorescence imaging; Fiber- och polymervetenskap; Fibre and Polymer Science;

   Abstract : Most of the devastating diseases such as cancer are relatively incurable and have high risks of relapse. Therefore, persistent endeavors have been devoted to improve patient survival rate and quality of life. READ MORE

7. 5. Lipid-based liquid crystals as drug delivery vehicles for antimicrobial peptides

   Author : Lukas Boge; Martin Andersson; Lovisa Ringstad; RISE; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Liquid crystals; liquid crystalline nanoparticles; cubosome; hexosome; phase behavior; antimicrobial peptide; AMP; glycerol monooleate; proteolysis; antimicrobial effect; antimicrobial resistance; bacterial membrane; membrane interaction; infection; topical delivery; pulmonary delivery;

   Abstract : The development of antimicrobial resistance is a great challenge within health sectors worldwide. Thus, demand for new, efficient treatments is urgent in order to treat various bacterial infections. Antimicrobial peptides (AMPs) are a group of antibiotics that have gained more and more attraction in the past decade. READ MORE