Search for dissertations about: "ekberg"

Showing result 1 - 5 of 59 swedish dissertations containing the word ekberg.

  1. 1. Free-energy studies of ligand-binding affinities

    Author : Vilhelm Ekberg; Beräkningskemi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; free energy perturbation; drug design; ligand-binding affinity; entropy; molecular mechanics; molecular dynamics;

    Abstract : In drug discovery, it is of utmost importance to accurately calculate the free energies of binding ligands to various protein targets, such as enzymes and receptors. We have assessed and used computational tools for this aim, most of them based on molecular dynamics (MD) simulations. READ MORE

  2. 2. Uncertainty and sensitivity analyses of chemical modelling applied to a repository for spent nuclear fuel

    Author : Christer Ekberg; Chalmers tekniska högskola; []
    Keywords : sensitivity analysis; Latin Hypercube sampling; Monte Carlo sampling; solubility; uncertainty analysis;

    Abstract : .... READ MORE

  3. 3. Treatment of Temporomandibular Disorders of Arthrogeneous Origin. Controlled double-blind studies of a non-steroidal anti-inflammatory drug and a stabilisation appliance

    Author : EwaCarin Ekberg; Institutionen för hälsovetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Temporomandibular Joint Disorders; Randomized Controlled Trials; Non-steroidal Anti-inflammatory Agents; Occlusal Splints; Treatment Outcome; Mandibular Condyle Radiography; Subtraction Technique; Radiographic Image Enhancement; Causality; Odontology; stomatology; Odontologi;

    Abstract : The aim of this thesis was to prospectively evaluate the short-term effect of a non-steroidal anti-inflammatory drug (diclofenac sodium, Voltaren) and stabilisation appliance in controlled trials of patients with temporomandibular disorders (TMD) of arthrogeneous origin. The active treatments were compared to placebo in the study of diclofenac and to a control appliance in the other study. READ MORE

  4. 4. Kinetic studies of the decomposition of some carbamates, ureas and related cyclic compounds

    Author : Gudrun Ekberg; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PHARMACY; FARMACI;

    Abstract : .... READ MORE

  5. 5. Cyclin A1 Expression and Regulation in Hematopoietic and Leukemic Cells

    Author : Jenny Ekberg; Malmö Patologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer; General pathology; pathological anatomy; Patologi allmän ; patologisk anatomi; onkologi; Cytologi; cancerology; oncology; Cytology; AML; cyclin A1; apoptosis; cell cycle regulation;

    Abstract : Increased expression of the cell cycle regulatory protein cyclin A1 has previously been detected in patients with acute myeloid leukemia (AML) and targeted overexpression of cyclin A1 in a transgenic mouse model initiated AML. The aim of this thesis was to further study the expression and regulation of cyclin A1 in hematopoietic cells. READ MORE