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Showing result 1 - 5 of 16 swedish dissertations matching the above criteria.
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1. High Rate Electron Capture Dissociation Fourier Transform Ion Cyclotron Resonance Mass Spectrometry
Abstract : Advances in science and technology during the past decade have greatly enhanced the level of the structural investigation of macromolecules – peptides and proteins. Biological mass spectrometry has become one of the most precise and sensitive techniques in peptide and protein analysis. READ MORE
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2. Ultrafast Photoionization Dynamics Studied with Coincidence Momentum Imaging Spectrometers
Abstract : The time scale of the dynamics in atoms and molecules varies from attoseconds (10-18) to picoseconds (10-12) depending on the size of the particles. To study such dynamics, ultrafast light pulses are needed to trigger and capture the reaction. One of the most direct methods consists in ionizing the system and observing the following response. READ MORE
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3. Secondary and Higher Order Structural Characterization of Peptides and Proteins by Mass Spectrometry
Abstract : The work in this thesis has demonstrated the advantages and limitations of using MS based technologies in protein and peptide structural studies. Tandem MS, specifically electron capture dissociation (ECD) have shown the ability to provide structural insights in molecules containing the slightest of all modifications (D-AA substitution). READ MORE
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4. Characterization of Polypeptides by Tandem Mass Spectrometry Using Complementary Fragmentation Techniques
Abstract : In the growing field of proteomics identification of proteins by tandem mass spectrometry (MS/MS) is performed by matching experimental mass spectra against calculated spectra of all possible peptides in a protein database. One problem with this approach is the false-positive identifications. READ MORE
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5. Identification and Characterization of Peptides and Proteins using Fourier Transform Ion Cyclotron Resonance Mass Spectrometry
Abstract : Mass spectrometry has in recent years been established as the standard method for protein identification and characterization in proteomics with excellent intrinsic sensitivity and specificity. Fourier transform ion cyclotron resonance is the mass spectrometric technique that provides the highest resolving power and mass accuracy, increasing the amount of information that can be obtained from complex samples. READ MORE