Search for dissertations about: "electron capture dissociation"

Showing result 6 - 10 of 16 swedish dissertations containing the words electron capture dissociation.

  1. 6. Analysis of Complex Biological Samples using Liquid Chromatography-Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

    Author : Margareta Ramström; Jonas Bergquist; Per Håkansson; Karin Markides; Carol Robinson; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Analytical chemistry; mass spectrometry; liquid chromatography; protein; proteomics; peptide; Fourier transform ion cyclotron resonance mass spectrometry; cerebrospinal fluid; amyotrophic lateral sclerosis; electrospray ionization; electron capture dissociation; Analytisk kemi; Analytical chemistry; Analytisk kemi;

    Abstract : Studies of protein and peptide expression are vital in order to understand complex biological systems. As demonstrated in this thesis, on-line packed capillary liquid chromatography-Fourier transform ion cyclotron resonance mass spectrometry (LC-FTICR MS) is a useful analytical tool for such studies. READ MORE

  2. 7. Electron-Ion Recombination in Atmospheric and Laboratory Plasmas

    Author : Anneli Ehlerding; Mats Larsson; Ursel Fantz; Stockholms universitet; []
    Keywords : ;

    Abstract : In this thesis, the measurements performed at CRYRING, Stockholm University, on the dissociative recombination of C2H+, C2H4+, C2D5+, C3H7+, C3D7+, C4D9+, Na+(D2O), CF+, CF2+ and CO2+ are presented. The dissociative recombination is the reaction in which a positive molecular ion captures an electron and stabilizes the capture by dissociation into neutral fragments. READ MORE

  3. 8. Activation of the spike proteins of alpha- and retroviruses

    Author : Shang-Rung Wu; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Alphavirus; Retrovirus; Fusion protein; electron cryomicroscopy; intermediate structure;

    Abstract : Enveloped viruses like human immunodeficiency virus type 1 (HIV-1) enter cells by fusing their membrane with that of the cell plasma membrane, while others, like influenzavirus and alphavirus enter via uptake into endosomes and fusion with the endosomal membrane. For this they carry spike proteins. READ MORE

  4. 9. The dynamic envelope of a fusion class II virus : molecular reorganizations during prefusion stages of Semliki forest virus

    Author : Lars Haag; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Alphavirus; SFV; fusion; cryo-EM; formaldehyde; reorganization; cross-link; 3D reconstruction; acid pH; Pepscan; MAb; inactivation; dissociation; monoclonal antibody;

    Abstract : The aim of this study was to explore a membrane fusion mechanism, prevailing in alphaviruses and known as virus class 11 fusion. The model virus for this mechanism is Semliki Forest virus (SFV) of the alphavirus family. READ MORE

  5. 10. Fragmentation of Amino Acids and Microsolvated Peptides and Nucleotides using Electrospray Ionization Tandem Mass Spectrometry

    Author : Henrik Johansson; Henning Schmidt; Henrik Cederquist; Jens Jensen; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Atomic and molecular physics; Atom- och molekylfysik; fysik; Physics;

    Abstract : This thesis presents three different series of high energy (keV) collision experiments as well as a brief scientific introduction to the field. In the first series, protonated glycine and leucine were collided with carbon dioxide and a beam attenuation method was applied to determine their total fragmentation cross sections. READ MORE