Search for dissertations about: "electrophysiology"

Showing result 11 - 15 of 93 swedish dissertations containing the word electrophysiology.

  2. 11. CRISPR/Cas9-based therapies and the role of astrocytes in Alzheimer’s disease and Parkinson’s disease

    Author : Evangelos Konstantinidis; Martin Ingelsson; Anna Erlandsson; Vilmantas Giedraitis; Magnus Essand; Harald Steiner; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer s disease; Parkinson s disease; gene editing; CRISPR Cas9; amyloid-beta; astrocytes; neurons; iPSCs; electrophysiology;

    Abstract : Alzheimer’s disease (AD) and Parkinson’s disease (PD) are the two most common neurodegenerative disorders. Whereas the AD brain features plaques of amyloid-beta (Aβ) and neurofibrillary tangles of tau, the PD brain is characterized by Lewy bodies and Lewy neurites containing α-synuclein (αSyn). READ MORE

  4. 12. Neural Interfaces to the Odour World of Scarab Beetles

    Author : Mattias Larsson; Biologiska institutionen; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Djurekologi; Animal ecology; Intra; Antennal lobe; CNS; Attraction; Olfactometer; Behaviour; Mass spectrometry; Gas chromatography; Electrophysiology; Single sensillum; Receptor neuron; Plant volatile; Sex pheromone; Neuroethology; Odour detection; Olfaction; Coleoptera; Scarabaeidae; Entomology; plant parasitology; Entomologi; växtparasitologi; Environmental chemistry; Miljökemi;

    Abstract : Antennal detection and central nervous integration of behaviourally relevant odours in scarab beetles (Coleoptera: Scarabaeidae) was investigated, using the two Japanese scarabs Anomala cuprea and Phyllopertha diversa (Rutelinae), and the Central African fruit chafer Pachnoda marginata (Cetoniinae) as model species. Electrophysiological single cell recordings in A. READ MORE

  5. 13. Endogenous modulators of hyperexcitability in epilepsy: electrophysiological and optogenetic delineation of neuropeptide Y mechanisms in interneurons

    Author : Marco Ledri; Lund Neurologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; interneurons; Epilepsy; Neuropeptide Y; synaptic transmission; synaptic plasticity; electrophysiology; optogenetics;

    Abstract : Epilepsy is one of the most common neurological disorders worldwide, affecting 1% of the general population, and is characterized by a predisposition for the generation of epileptic seizures. Despite having several different aetiologies, a common underlying cause of epilepsy seems to be an acquired imbalance between excitatory and inhibitory circuits in the brain, which leads to hyperexcitability and appearance of seizures. READ MORE

  6. 14. Acute coronary syndromes. The prognostic importance of hypertension, diabetes and vectorcardiographic markers

    Author : Markus Lingman; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; acute coronary syndromes; hypertension; diabetes; percutaneous coronary intervention; prognosis; myocardial ischemia; coronary artery disease; electrocardiography; vectorcardiography; arrhythmia; sudden death; electrophysiology;

    Abstract : Research questions: 1 Is hypertension and diabetes associated with the future risk of death, and recurrent manifestations of cardiovascular disease in acute coronary syndromes (ACS)? 2 How does myocardial ischemia affect depolarization and repolarization of the heart during the early phase of an acute myocardial infarction? 3 What is the prognostic value of accepted vectorcardiographic markers in relation to future risk of sudden cardiac death after ACS? Methodology: Papers I, III and IV studied patients with ACS prospectively and consecutively included at the coronary care unit of Sahlgrenska University Hospital. Paper I deals with 2,329 patients who were followed for a median of 8 years. READ MORE

  7. 15. Bitcoding the brain. Integration and organization of massive parallel neuronal data

    Author : Bengt Ljungquist; Neuronano Research Center (NRC); []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuroinformatics; electrophysiology; neurons;

    Abstract : .... READ MORE