Search for dissertations about: "embryo toxicity"

Showing result 1 - 5 of 13 swedish dissertations containing the words embryo toxicity.

  2. 1. Comparative avian developmental toxicity of PFAAs

    Author : Marcus Nordén; Magnus Engwall; Krister Halldin; Anders Bignert; Örebro universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; chicken; herring gull; cormorant; PFAA; PFOS; PFOA; toxicity; levels; Biology; Biologi;

    Abstract : Perfluoroalkyl acids (PFAAs) are persistent organic pollutants that can commonly be found in environmental matrixes and wildlife from all over the globe. The PFAAs have been used in applications such as water and dirt repelling treatments for textiles, oil-resistant paper coatings and fire-fighting foams. READ MORE

  4. 2. Improved environmental monitoring and assessment : Establishing links between effects of chemical pollution at different levels of biological organization in a Baltic Sea bioindicator species (Monoporeia affinis)

    Author : Martin Reutgard; Magnus Breitholtz; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Environmental health assessment; environmental monitoring; chemical pollution; hypoxia; bioindicators; biomarkers; teratogenicity; embryo toxicity; oxidative stress; acetylcholine esterase. Monoporeia affinis; Baltic Sea; Applied Environmental Science; tillämpad miljövetenskap;

    Abstract : A large number of chemicals enters the marine environment via atmospheric deposition, run-off, rivers and streams, industrial effluents and municipal wastewater. To understand how chemicals affect environmental health, monitoring and assessment approaches need to combine physical, chemical and biological effect parameters from different levels of biological organization. READ MORE

  5. 3. Toxicometabolomics and biotransformation product screening in single zebrafish embryos

    Author : Anton Ribbenstedt; Jonathan P. Benskin; Magnus Breitholtz; Elena Gorokhova; Emma Schymanski; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Non-target; REACH; Orbitrap; single embryo; zebrafish embryo; metabolism; high throughput; hydroxylation; glucuronidation; metabolite screening; phase I; phase II; pharmaceutical; structure elucidation; conjugation; propranolol; beta blocker; Non-targeted; toxicometabolomics; Orbitrap; single embryo; 3R; metabolomics; MoA; mode of action; zebrafish embryo; carbamazepine; biotransformation; Applied Environmental Science; tillämpad miljövetenskap;

    Abstract : Over the last decade environmental agencies worldwide have escalated their work to phase out animal testing for the purposes of chemical regulation. Meanwhile the number of commercially available chemicals and the requirements for hazard assessments have both increased, creating a large need for substitution of traditional in vivo assays with in vitro tests. READ MORE

  6. 4. Application and interpretation of biomarkers in ecotoxicology - from molecular to individual level responses

    Author : Sara Furuhagen; Elena Gorokhova; Carlos Barata; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; biomarkers; oxidative stress; ORAC; reproduction; Daphnia magna; toxicity; environmental stress; Applied Environmental Science; tillämpad miljövetenskap;

    Abstract : The use of biomarkers is considered a promising alternative, or complement, to traditional ecotoxicological assays. Toxic effects are often initially manifested at the molecular or biochemical level, biomarkers are therefore used as sensitive indicators of toxic exposure. READ MORE

  7. 5. Biomarkers and bioindicators of hypoxia and sediment toxicity in Monoporeia affinis

    Author : Marie Löf; Brita Sundelin; Tina Elfwing; Elena Gorokhova; Ingela Dahllöf; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biomarkers; Bioindicators; Embryo aberrations; Hypoxia; Contaminated sediment; PAHs; PCBs; Metals; Baltic Sea; Amphipods; Monoporeia affinis; Applied Environmental Science; tillämpad miljövetenskap;

    Abstract : Two of the most pressing environmental problems in the Baltic Sea are pollution and oxygen deficiency. The aim of this doctoral thesis was to evaluate a set of biomarkers and reproductive variables in the amphipod Monoporeia affinis to test their suitability as indicators of exposure to contaminants and hypoxia. READ MORE