Search for dissertations about: "emma persson"

Showing result 1 - 5 of 7 swedish dissertations containing the words emma persson.

2. 1. The breast cancer microenvironment and cancer cell secretion - specific effects on cancer progression and subtypes of cancer cells

   Author : Emma Persson; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; cancer microenvironment; secretion; hypoxia;

   Abstract : Breast cancer is the cancer form responsible for the most cancer-related deaths among women worldwide, and novel targeted therapies are highly needed. The tumor microenvironment consists of several components, including different cell types, extracellular matrix, oxygen and nutrient gradients and soluble factors that plays a key role in cancer progression. READ MORE

4. 2. The ontogeny and function of intestinal dendritic cells

   Author : Emma Persson; Slemhinnans immunologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mesenteric lymph nodes; Intestine; Dendritic cells; Gut-homing; Th17 cells; Oral tolerance; Immunity;

   Abstract : The intestinal mucosa presents a huge surface area to the external environment and the intestinal immune system is continually exposed to a wide array of foreign antigens derived from resident intestinal microbiota as well as dietary constituents, including food proteins. In order to maintain intestinal homeostasis, the intestinal immune system relies on the ability to generate tolerogenic responses to innocuous antigen while maintaining the ability to develop effective immune responses to intesinal pathogens. READ MORE

5. 3. Big data networks and orthology analysis

   Author : Emma Persson; Erik Sonnhammer; Albert László Barabási; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Ortholog; protein domain; functional association network; pathway enrichment analysis; biokemi med inriktning mot bioinformatik; Biochemistry towards Bioinformatics;

   Abstract : Understanding biological systems in complex organisms is important in life science in order to comprehend the interplay of genes, proteins, and compounds causing complex diseases. As biological systems are intricate, bioinformatics tools, models, and algorithms are of the utmost importance to understand the bigger picture and decipher biological meaning from the vast amounts of information available from biological experiments and predictions. READ MORE

6. 4. Causal inference and case-control studies with applications related to childhood diabetes

   Author : Emma Persson; Ingeborg Waernbaum; Xavier de Luna; Gisela Dahlquist; Stijn Vansteelandt; Umeå universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; covariate selection; design-weighted estimation; marginal effect; matching; register study; treatment effect; type 1 diabetes mellitus; Statistics; statistik;

   Abstract : This thesis contributes to the research area of causal inference, where estimation of the effect of a treatment on an outcome of interest is the main objective. Some aspects of the estimation of average causal effects in observational studies in general, and case-control studies in particular, are explored. READ MORE

7. 5. The neuropeptide VIP and the IL-6 family of cytokines in bone : effects on bone resorption, cytokine expression and receptor signalling in osteoblasts and bone marrow stromal cells

   Author : Emma Persson; Ulf Lerner; Andreas Kindmark; Umeå universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; osteoblast; bone resorption; cytokines; IL-6; neuropeptides; VIP; transcription factor; Cell biology; Cellbiologi;

   Abstract : Bone tissue is continuously degraded and rebuilt to respond to the needs of the body. Cells of the osteoblast lineage are responsible for the formation of bone, whereas the resorption of bone tissue is carried out by osteoclasts. READ MORE