Search for dissertations about: "enantiomeric ratio"

Showing result 1 - 5 of 9 swedish dissertations containing the words enantiomeric ratio.

  2. 1. Chiral building blocks for synthesis of pine sawfly sex pheromones Enantioselective Lipase Catalysed Acylations and Esterifications of Primary Alcohols and Acids and Synthesis of the Sex Pheromone of the Pine Sawfly Microdiprion pallipes

    Author : Ba-Vu Nguyen; KTH; []
    Keywords : lipase; Pseudomonas cepacia; Candida rugosa; enantioselective; enantiomeric ratio; primary 2-methylalcohol; substituted-methylcarboxylic acid; pine sawfly; Microdiprion pallipes; sex pheromone; 3; 7; 11-trimethyl-2-tridecanol; stereoisomer;

    Abstract : This thesis describes the development of new methods for thepreparation of enantiomerically pure methyl branched alkylcompounds and their use as building blocks in the synthesis ofstereoisomerically pure pheromones of pine sawflies.The high regioselectivity, enantioselectivity and activityof lipases in organic solvent in conjunction withenvironmentally compatible reaction conditions have madelipase-catalysed synthesis an attractive alternative toconventional synthetic methods in organic chemistry. READ MORE

  4. 2. Enthalpy and Entropy in Enzyme Catalysis : A Study of Lipase Enantioselectivity

    Author : Jenny Ottosson; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biocatalysis; enzyme catalysis; Candida antarctica lipase B; enantioselectivity; enthalpy; entropy; CALB; enantiomeric ratio; Bioengineering; Bioteknik;

    Abstract : Biocatalysis has become a popular technique in organic synthesis due to high activity and selectivity of enzyme catalyzed reactions. Enantioselectivity is a particularly attractive enzyme property, which is utilized for the production of enantiopure substances. READ MORE

  5. 3. Genetic influence on enantiomeric drug disposition : Focus on venlafaxine and citalopram

    Author : Maria Kingbäck; Fredrik Kugelberg; Björn Carlsson; Martin Josefsson; Finn Bengtsson; Johan Ahlner; Anders Rane; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : A molecule that is not identical to its mirror image is said to be chiral. A racemic mixture, or a racemate, is one that has equal amounts of S- and R-enantiomers of a chiral molecule. Two examples of frequently prescribed racemic drugs are the antidepressants venlafaxine (VEN) and citalopram (CIT). READ MORE

  6. 4. Enantiospecific Analysis and Environmental Behavior of Chiral Persistent Organic Pollutants (POPs)

    Author : Karin Wiberg; Umeå universitet; []
    Keywords : ;

    Abstract : Many persistent organic pollutants (POPs) are chiral. These pollutants are generally released into the environment as racemates, but frequently undergo alterations in enantiomeric composition as soon as they are subjected to life chemistry processes. READ MORE

  7. 5. Asymmetric transfer hydrogenation of aromatic ketones and azirines with NH-ligands

    Author : Peter Roth; Krister Zetterberg; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Organisk kemi; Organic chemistry; Organisk kemi; organisk kemi; Organic Chemistry;

    Abstract : The Ru(arene)[(1S, 3R, 4R)-3-(Hydroxymethyl)-2-azabicyclo[2.2.1]heptane catalyst was optimized as ligand in the asymmetric transfer hydrogenation of ketones and resulted in increased activity and enantioselectivity of the catalyst. READ MORE