Search for dissertations about: "endocrine treatment"

Showing result 1 - 5 of 212 swedish dissertations containing the words endocrine treatment.

  2. 1. Genetic Aspects of Endocrine Tumorigenesis : A Hunt for the Endocrine Neoplasia Gene

    Author : Alberto Delgado Verdugo; Peyman Björklund; gunnar westin; Per Hellman; Filip Farnebo; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Exome sequencing; SDHAF2; epigenetics; methylation; methylation array; Sanger sequencing; pheochromocytoma; SI-NETs; carcinoid; oncology; endocrine surgery; parathyroid; Genetics; Genetik; Kirurgi; Surgery;

    Abstract : Endocrine tumors arise from endocrine glands. Most endocrine tumors are benign but malignant variants exist. Several endocrine neoplasms display loss of parts of chromosome 11 or 18, produce hormones and responds poorly to conventional chemotherapeutics. The multiple endocrine neoplasia syndromes are mainly confined to endocrine tumors. READ MORE

  4. 2. Adjuvant treatments to prevent local reurrence after breast-conserving surgery for early breast cancer : radiation, endocrine- or brachytherapy

    Author : Åsa Wickberg; Göran Liljegren; Johan Ahlgren; Roger Olofsson Bagge; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast-conserving surgery; radiotherapy; endocrine therapy; intraoperative brachytherapy;

    Abstract : Radiotherapy after breast-conserving surgery due to breast cancer is an established treatment, known to reduce the incidence of recurrence and even death from the disease. However some women are over-treated with sometimes serious adverse effects. De-escalating the treatment and find alternative adjuvant methods are becoming an important issue. READ MORE

  5. 3. Endocrine disruption in fish : Effects of 17α-ethinylestradiol exposure on non-reproductive behavior, fertility and brain and testis transcriptome

    Author : Tove Porseryd; Inger Porsch Hällström; Ioanna Katsiadaki; Södertörns högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; 17α-ethinylestradiol; endocrine disrupting chemical; fish; behavior; fertility; transcriptome; RNA sequencing; Environmental Studies; Miljövetenskapliga studier; Östersjö- och Östeuropaforskning; Baltic and East European studies;

    Abstract : Aquatic environments are the end recipient for most anthropogenic chemical pollutants. One common chemical pollutant found in the aquatic environment is 17α-ethinylestradiol (EE2), a synthetic estrogen used in contraceptive pills. READ MORE

  6. 4. Pancreatic Endocrine Tumors and GIST - Clinical Markers, Epidemiology and Treatment

    Author : Sara Ekeblad; Britt Skogseid; Peter Stålberg; Barbro Eriksson; Rajesh Thakker; Uppsala universitet; []
    Keywords : Medicine; Pancreatic endocrine tumor; Gastrointestinal stromal tumor; Neuroendocrine; Multiple endocrine neoplasia type 1; Prognostic factors; Temozolomide; TNM staging; O6-methylguanine DNA methyltransferase; Growth hormone secretagogue receptor; Ghrelin; Medicin;

    Abstract : Pancreatic endocrine tumors and gastrointestinal stromal tumors are rare. Evidence regarding prognostic factors, and in the former also treatment, is scarce. We evaluated the survival and prognostic factors in a consecutive series of 324 patients with pancreatic endocrine tumors treated at a single institution. READ MORE

  7. 5. Cholesterol metabolism in breast cancer: Prognostic factors and optimizing treatment

    Author : Maria Inasu; Bröstcancer - prevention & intervention; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; Statins; Cholesterol; menopausal status; endocrine treatment; disease recurrence;

    Abstract : AbstractBreast cancer (BC) is the most common cancer among women in Sweden and worldwide. Adjuvant endocrine therapies are effective, yet 20-30% patients experience disease relapse. Altered cholesterol metabolism is an emerging hallmark of breast cancer proliferation and endocrine therapy resistance. READ MORE