Search for dissertations about: "enzymatic reactions"
Showing result 1 - 5 of 146 swedish dissertations containing the words enzymatic reactions.
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1. Quantum chemical modeling of enzymatic reactions : applications to the tautomerase superfamily
Abstract : In this thesis, quantum chemical methods are used to investigate enzymatic reaction mechanisms. The Density functional theory, in particular the hybrid B3LYP functional, is used to model two enzymes belonging to the tautomerase superfamily; 4-Oxalocrotonate Tautomerase (4-OT) and cis-Chloroacrylic Acid Dehalogenase (cis-CAAD). READ MORE
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2. 5-Aminolevulinic acid and derivatives thereof : properties, lipid permeability and enzymatic reactions
Abstract : 5-aminolevulinic acid (5-ALA) and derivatives thereof are widely usedprodrugs in treatment of pre-malignant skin diseases of the cancer treatmentmethod photodynamic therapy (PDT). The target molecule in 5-ALAPDTis protoporphyrin IX (PpIX), which is synthesized endogenously from5-ALA via the heme pathway in the cell. READ MORE
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3. Dynamic Systems : Enzymatic Synthesis, Exchange Reactions and Applications in Materials Science
Abstract : This thesis is divided into three parts, revolving around the developments of dynamic systems utilized in dynamic kinetic resolution (DKR) and constitutional dynamic chemistry (CDC).The first section gives an introduction to constitutional dynamics, the core concept of this thesis. READ MORE
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4. Quantum Chemical Modeling of Asymmetric Enzymatic Reactions
Abstract : Computational methods are very useful tools in the study of enzymatic reactions, as they can provide a detailed understanding of reaction mechanisms and the sources of various selectivities. In this thesis, density functional theory has been employed to examine four different enzymes of potential importance for biocatalytic applications. READ MORE
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5. Quantum Chemical Cluster Modeling of Enzymatic Reactions
Abstract : The Quantum chemical cluster approach has been shown to be quite powerful and efficient in the modeling of enzyme active sites and reaction mechanisms. In this thesis, the reaction mechanisms of several enzymes have been investigated using the hybrid density functional B3LYP. READ MORE