Search for dissertations about: "epidermal growth factor receptor"

Showing result 1 - 5 of 133 swedish dissertations containing the words epidermal growth factor receptor.

  2. 1. Androgen controlled regulatory systems in prostate cancer : potential new therapeutic targets and prognostic markers

    Author : Peter Hammarsten; Anders Bergh; Stina Häggström Rudolfsson; Pernilla Wikström; Sten Nilsson; Umeå universitet; []
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; prostate cancer; angiogenesis; human biopsy; androgen ablation; castration; prognostic marker; prognostic factor; growth control; VEGF; vascular endothelial growth factor; EGFR; epidermal growth factor receptor; pEGFR; phosphorylated EGFR; phosphorylated epidermal growth factor receptor; Pathology; Patologi;

    Abstract : BACKGROUND: Prostate cancer is by far the most common cancer among Swedish men. Some patients have an aggressive lethal disease, but the majority of affected men have long expected survival. Unfortunately, the diagnostic tools available are insufficient in predicting disease aggressiveness. Novel prognostic markers are therefore urgently needed. READ MORE

  4. 2. Receptors for growth hormone and prolactin. Regulation and activation

    Author : Gunnel Hellgren; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Growth hormone; GH receptor; Janus kinase; GH sensitivity; 5 -untranslated region; prolactin; prolactin receptor adipose tissue; liver; skeletal muscle; epidermal growth factor receptor; tyrosine kinase; kinase activity;

    Abstract : Cytokine receptor activation is dependent on ligand-induced receptor dimerization or oligomerization and subsequent activation of several intracellular proteins. Activation of Janus kinases (Jaks) is probably the first intracellular event that occurs after receptor dimerization. READ MORE

  5. 3. Biomarkers in non-small cell lung carcinoma : methodological aspects and influence of gender, histology and smoking habits on estrogen receptor and epidermal growth factor family receptor signalling

    Author : Christina Karlsson; Karin Piehl-Aulin; Ulf Tidefelt; Gisela Helenius; Leif Johansson; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Non-small cell lung carcinoma; estrogen receptor; epidermal growth factor receptor; HER-4; tissue microarray; immunohistochemistry; smoking habits; in situ hybridisation; Onkologi; Oncology;

    Abstract : Non-small cell lung carcinoma is a leading cause of cancer mortality worldwide. There are gender and smoking associated differences both in tumour types and clinical outcome. Squamous cell carcinomas (SCC) are more frequent among smoking men while females develop adenocarcinomas (ADCA). READ MORE

  6. 4. Pancreatic Growth and Secretion. An Experimental Study on Growth Factors in Rat and Mouse

    Author : Claes Hjalmarsson; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; oncology; Cytology; PBD; insulin; B-cells; bile; pancreatic cancer; intestine; secretion; pancreas; proliferation; tyrphostins; CCK; epidermal growth factor; transforming growth factor alpha; cancerology; Cytologi; onkologi; cancer; Surgery; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi;

    Abstract : The pancreas is a central organ in the digestion of food as well as in glucose metabolism. Its two major functions are exocrine and endocrine secretion. READ MORE

  7. 5. Novel Methods for Analysis of Heterogeneous Protein-Cell Interactions : Resolving How the Epidermal Growth Factor Binds to Its Receptor

    Author : Hanna Björkelund; Karl Andersson; Lars Gedda; Yosef Yarden; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Heterogeneity; Kinetics; EGFR; HER2; LigandTracer; Interaction Map; Internalization; Specificity; Medical Science; Medicinsk vetenskap;

    Abstract : Cells are complex biological units with advanced signalling systems, a dynamic capacity to adapt to its environment, and the ability to divide and grow. In fact, they are of such high level of complexity that it has deemed extremely difficult or even impossible to completely understand cells as complete units. READ MORE