Search for dissertations about: "epithelial-mesenchymal interaction"

Found 4 swedish dissertations containing the words epithelial-mesenchymal interaction.

  1. 1. A functional genomics approach to PDGF and pericyte biology

    Author : Cecilia Bondjers; Göteborgs universitet.; University of Gothenburg.; [2003]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN; MEDICINE; PDGF; hair follicle; skin; testis; epithelial-mesenchymal interaction; microarray; pericyte; transgenic mouse;

    Abstract : The rapid expansion of genome sequence data demands for increased efforts and speed concerning functional analysis of gene products. Two approaches to such analysis, namely transgenic technologies and analysis of gene expression have successfully been used to study functions of gene products in complex organisms, such as mammals. READ MORE

  2. 2. Functions of PDGF-A and -C. Essential ligands for the PDGF alpha receptor

    Author : Hans Boström; Göteborgs universitet.; University of Gothenburg.; [2003]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biokemi; Biochemistry; Medicinsk cellbiologi; Medical cell biology; platelet-derived growth factor; PDGF-A; PDGF-C; PDGF alpha receptor; extracellular retention; gene targeting; mouse development; epithelial-mesenchymal interaction; lung; alveolar formation; spina bifida; gastrointestinal villus;

    Abstract : Altered protein kinase activity is a contributing factor in many diseases including most formsof human malignancies, and there is reason to believe that protein kinases will prove to be majordrug targets in the treatment of cancer. Protein kinases mediate most of the signal transduction ineukaryotic cells, regulating cellular events such as transcription, metabolism, proliferation,cytoskeletal rearrangement, migration, differentiation and apoptosis. READ MORE

  3. 3. Molecular and Cellular Control of Palate Development in the Mouse

    Author : Forugh Vaziri Sani; Göteborgs universitet.; University of Gothenburg.; [2008]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ODONTOLOGI; ODONTOLOGY; cleft palate; fate mapping; Sonic hedgehog; apoptosis; extracellular matrix; mouse;

    Abstract : The formation of a definitive secondary palate in mammals is a multistep process that comprises growth, elevation, contact and fusion of the two palatal shelves. Disruption at any step generates cleft palate, a major congenital birth defect. Therefore, it is important to understand the mechanisms governing normal palate development. READ MORE

  4. 4. Signal integration between notch and hypoxia : insights into development and disease

    University dissertation from Stockholm : Karolinska Institutet, Department of Cell and Molecular Biology

    Author : Maria Gustafsson; Karolinska Institutet.; Karolinska Institutet.; [2007]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Oxygen is essentially required for aerobic metabolism in most eukaryotic organisms. Therefore, it is striking that a number of tissues develop, and are maintained at low oxygen (hypoxic) conditions in the body. For instance, the human embryo is located in a hypoxic environment. READ MORE