Search for dissertations about: "esophagus cancer"

Showing result 1 - 5 of 33 swedish dissertations containing the words esophagus cancer.

  2. 1. Genomic Profiling, Mutations and Deranged Signaling in Esophageal Cancer and Hereditary Colorectal Cancer

    Author : Anna Isinger Ekstrand; Institutionen för immunteknologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Esophageal cancer; hereditary cancer; HNPCC; copy number analysis; CGH; gene expression; Wnt; PIK3CA; CHEK2; gastric cancer; colorectal cancer;

    Abstract : Esophageal cancer and colorectal cancer represents two major types of gastrointestinal tumors. Though refined surgery and introduction of novel chemotherapeutics have improved outcome, more than 2500 Swedes die from these diseases every year. Novel markers for early diagnosis, prognosis and treatment prediction are therefore needed. READ MORE

  4. 2. Nuclear medicine imaging of lung cancer and esophagus cancer

    Author : Gunnar Herlin; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Lung cancer;

    Abstract : Background: Somatostatin receptors (SSTRs) occur in cancer tissue, and 99mTc-depreotide is a labelled somatostatin receptor analogue, binding to SSTRs subtype 2, 3, and 5. Purpose: The general aim of the present thesis was to study somatostatin receptor scintigraphy (SSTRS) with 99mTc-depreotide in the diagnosis and characterization of cancers in the lung and oesophagus. READ MORE

  5. 3. The Columnar Lined Esophagus. Pathophysiological and Clinical Aspects

    Author : Stefan Öberg; Lund Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Intestinal metaplasia; Barrett s esophagus; Esophageal columnar metaplasia; Metaplasia; Pathophysiology; Gastroesophageal reflux disease; Esophagus; Surgery; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi;

    Abstract : There is a persisting controversy concerning the definition, etiology and pathogenesis of Barrett's esophagus. The dramatic and parallel increase in the incidence of esophageal and junctional adenocarcinoma over the past decades justifies an evaluation of the pathophysiology of premalignant metaplastic changes of the esophagus and the gastroesophageal junction. READ MORE

  6. 4. Computational Modelling of Gene Regulation in Cancer : Coding the noncoding genome

    Author : Husen Muhammad Umer; Jan Komorowski; Claes Wadelius; Jan Korbel; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Regulatory elements; gene regulation; cancer; motif; integrative database; software solutions for cancer data; Bioinformatics; Bioinformatik;

    Abstract : Technological advancements have enabled quantification of processes within and around us. The information stored within our body converts into petabytes of data. Processing and learning from such data requires comprehensive computational programs and software systems. READ MORE

  7. 5. Biological Functions of Iduronic Acid in Chondroitin/Dermatan Sulfate in Tumor and Brain Development

    Author : Martin Thelin; Matrixbiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; iduronic acid; chondroitin sulfate; esophagus squamous cell carcinoma; cancer; MET receptor; dermatan sulfate; hepatocyte growth factor; DS-epimerase 2; DS-epimerase 1;

    Abstract : Cell behavior such as migration and proliferation, especially during cancer development, are balanced by the surrounding environment. Complex polysaccharides called glycosaminoglycans (GAGs) are part of this environment and they are known to modulate tumor development. READ MORE