Search for dissertations about: "estrogen receptor alpha"

Showing result 1 - 5 of 51 swedish dissertations containing the words estrogen receptor alpha.

  1. 1. Expression and function of vascular estrogen receptors alpha and beta

    University dissertation from Min Liang, BMC F12, 221 84 Lund, Sweden

    Author : Min Liang; Lunds universitet.; Lund University.; [2004]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endocrinology; secreting systems; diabetologi; diabetology; Endokrinologi; sekretion; ubiquitin-proteasome pathway; MIP-2; MCP-1; iNOS; estrogen receptor knockout; estrogen receptor; aorta; estrogen;

    Abstract : Popular Abstract in Swedish Det kvinnliga könshormonet östrogen utövar sin effekt via två bindningsprotein (receptorer) benämnda ERa och ERb. Då östrogen binder till receptorn aktiverar alternativt inaktiverar detta komplex sekvenser av DNA molekylen. READ MORE

  2. 2. Erythropoietin receptor in growth control and anti-estrogen resistance of estrogen receptor positive breast cancer

    University dissertation from Department of Laboratory Medicine, Lund University

    Author : Susann Reinbothe; Lunds universitet.; Lund University.; [2015]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tamoxifen resistance; proliferation; PI3k pathway; Breast cancer; erythropoietin receptor; estrogen receptor;

    Abstract : The main function of Erythropoietin (EPO) and its receptor (EPOR) is the stimulation of erythropoiesis. Therefore, recombinant human EPO (rhEPO) is used to treat anemia in cancer patients, but some studies have reported that rhEPO treatment might promote tumor progression. Additionally, EPOR expression has been detected in various cancer forms. READ MORE

  3. 3. Estrogen receptor alpha and beta in breast cancer - gene expression profiles and clinical implications

    University dissertation from Department of Oncology, Clinical Sciences, Lund University

    Author : Sofia Gruvberger; Lunds universitet.; Lund University.; [2005]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk biologi; oncology; cancerology; Cytologi; onkologi; cancer; Cytology; artificial neural networks; gene expression profiling; microarray; tamoxifen; adjuvant endocrine therapy; ER; estrogen receptor beta; Breast cancer; estrogen receptor alpha; Clinical biology;

    Abstract : Breast cancer is the most common malignancy in women in the Western world with about 10% of women developing breast cancer during their lifetime, of which one third will eventually succumb to the metastatic form of the disease. Breast cancer arises from the epithelial cells of the breast mammary gland, but the mechanisms involved in tumor initiation, progression, and metastasis are still not fully understood. READ MORE

  4. 4. The role of estrogen receptor alpha in the regulation of bone and growth plate cartilage

    University dissertation from Department of Oncology, Clinical Sciences, Lund University

    Author : Anna E Börjesson; Göteborgs universitet.; Gothenburg University.; [2012]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; estrogen receptor α; bone; growth plate; estrogen;

    Abstract : Estrogens are important endocrine regulators of skeletal growth and maintenance in both females and males. Studies have demonstrated that the estrogen receptor (ER)-α is the main mediator of these estrogenic effects in bone. Therefore, estrogen signaling via ERα is a target both for affecting longitudinal bone growth and for bone remodeling. READ MORE

  5. 5. Muscles, Estrogen, and Bone

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Eva Ljunggren Ribom; Uppsala universitet.; [2003]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Muscle strength; Bone mineral density; Ultrasound; Body composition; Hormone replacement therapy; Estrogen receptor alpha; Kirurgi; MEDICINE Surgery; MEDICIN Kirurgi;

    Abstract : Sweden has one of the highest incidences of osteoporotic fractures in the world. A more sedentary lifestyle is one of several proposed reasons for the increase in osteoporosis seen in the developed countries. READ MORE