Search for dissertations about: "estrogen receptor alpha"

Showing result 6 - 10 of 61 swedish dissertations containing the words estrogen receptor alpha.

  2. 6. Role of estrogen receptor beta in epithelia lacking estrogen receptor alpha expression

    Author : Andrea Morani; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Estrogen Receptors; Extracellular Matrix; Prostate Cancer; Lung Diseases; Ovarian Follicle;

    Abstract : Estrogens influence the physiology of many organs by activation of the nuclear receptors ERalpha and ERbeta. The epithelium of ventral prostate, ovarian granulosa cells and lung, are ERalpha-negative but express high levels of ERbeta. This thesis focuses on the role played by ERbeta in ERalpha-negative epithelium. READ MORE

  4. 7. Estrogen receptors and inflammation in colorectal cancer. Role in prognosis and therapeutic opportunities

    Author : Geriolda Topi; Malmö Cellpatologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Colorectal Cancer; Estrogen Receptor alpha; Estrogen receptor beta; Prognosis and survival; Zebrafish; Metastasis; ERB-041; PPT; AZD9496; Mast cells; Cysteinyl leukotriene receptors;

    Abstract : .... READ MORE

  5. 8. Polymorphism in sex steroid-related genes. Effects on hormone levels and behavior

    Author : Lars Westberg; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; sex steroids; androgen receptor; estrogen receptor; progesterone receptor; polymorphism; genetics; association study; prolactin; personality; premenstrual dysphoric disorder; Parkinson s disease;

    Abstract : Genetic factors are important for variations between individuals with respect to most humantraits and diseases. Sex steroids are of profound importance for reproduction, metabolism,cardiovascular function and bone formation. They are potent regulators of their ownsynthesis as well as of that of other hormones, including prolactin. READ MORE

  6. 9. Breast Cancer Biomarkers with Clinical Relevance Identified by Massively-parallel DNA and RNA Sequencing

    Author : Malin Dahlgren; Translational Oncogenomics; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; DNA sequencing; RNA sequencing; Metastasis; Biomarker; Estrogen receptor alpha; Estrogen receptor beta; ESR1; ESR2; Breast cancer; DNA sequencing; RNA sequencing; metastasis; biomarker; Estrogen receptor alpha; Estrogen receptor beta; ESR1; ESR2;

    Abstract : Women have a 10% lifetime risk of developing breast cancer, and the disease has surpassed lung cancer as the most frequently diagnosed type of cancer in the world. Breast cancer originates in the epithelial cells of the mammary gland and tumor cells have undergone a series of genetic and phenotypic changes that confer tumor promoting properties. READ MORE

  7. 10. Estrogen receptor signalling in mammary epithelial cells

    Author : Malin Hedengran Faulds; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ER; STAT5; mammary epithelial cell differentiation; EGF; DAX-1;

    Abstract : The mammary gland is a complex tissue going through cycles of extensive proliferation and differentiation. Many hormones are involved in the regulation of development of the mammary gland, including estrogen, prolactin and epidermal growth factor (EGF). READ MORE