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Found 4 swedish dissertations matching the above criteria.

  1. 1. Building the Bridge from Bench to Bedside: Ethical Issues in Translational Stem Cell Research

    Author : Kristina Hug; Medicinsk etik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Translational stem cell research; research ethics; values; experimental stem cell-based therapies; patient safety; treatment efficacy; treatment accessibility; first-in-human trials; Parkinson’s disease; Huntington’s disease; priority setting; right to withdraw; human biological material; informed consent;

    Abstract : Abstract in UndeterminedTranslational stem cell research raises many interesting ethical questions, which have, to a greater or lesser degree, been debated at an international as well as at an interdisciplinary level. Nevertheless, there is still no international consensus regarding how a number of ethical questions related to this research should be answered. READ MORE

  2. 2. Derivation, Characterization and Differentiation of Feeder-Free Human Embryonic Stem Cells

    Author : Narmin Bigdeli; Göteborgs universitet; []
    Keywords : Embryonic Stem Cells; Differentiation;

    Abstract : Human embryonic stem cells (hESCs) are pluripotent cells with self-renewal ability, derived from the inner cell mass of a human blastocyst. They have the remarkable potential to develop into different cell types and can thus be used to regenerate and restore damaged tissues and organs in the entire body. READ MORE

  3. 3. Clinical Findings and Outcome after Stroke. Including a Translational Stem Cell Therapy Perspective

    Author : Hossein Delavaran; Lund Neurologi; []
    Keywords : stroke; recovery; outcome; cognitive function; Upper extremity motor impairment; Stem cell therapy;

    Abstract : Background and Purpose: Stroke is one of the dominant causes of death and adult disability in the world. There is a need for novel therapeutic approaches to improve functional recovery and outcome after stroke, and experimental studies have shown that stem cell-based therapies (SCT) hold much potential in this regard. READ MORE

  4. 4. Chemogenetics, Induced Neurons and Pluripotent Stem Cells: Towards Advanced Gene and Cell Therapies Targeting Epilepsy

    Author : Natalia Avaliani; Epilepsicentrum; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Chemogenetics; iPS; iN; electrophysiology; gene and cell therapy; Epilepsy;

    Abstract : The complexity of the central nervous system and existence of the blood-brain barrier often causes difficulties for traditional pharmacological treatments of neurological diseases. This thesis explores the feasibility and potential for novel gene and cell therapy approaches, which hold better promise for neurological disorders, while particularly targeting epilepsy. READ MORE