Search for dissertations about: "expression method"

Showing result 1 - 5 of 952 swedish dissertations containing the words expression method.

2. 1. Expression profiling using manifold supports

   Author : Anette Hagberg; Joakim Lundeberg; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; mRNA; expression; minimal residual disease MRD ; chronic myeloid leukemia CML ; recombinant human erythropoietin r-HuEpo ; anemia; insulin dependent diabetes mellitus IDDM ; transplantation; Genetik; Clinical genetics; Klinisk genetik; Medical Genetics; medicinsk genetik;

   Abstract : Analyses of mRNA provides a condensed view of gene structure and quantitative analysis can reveal the induction of physiological or pathological gene expression programs. This thesis describes a new method for mRNA isolation, followed by sensitive real time detection via polymerase chain reaction (PCR), in order to quantitate transcripts of interest. READ MORE

4. 2. Potential Flow Panel Methods for the Calculation of Free-surface Flows with Lift

   Author : Carl-Erik Janson; Chalmers tekniska högskola; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; desingularized; shape optimization; Rankine source; waves; OCTOPUS; dipole; MMA; Dawson operator; boundary layer; vortex; Method of Moving Asymptotes; nonlinear; sailing yacht; four point operator; surface piercing wing; Navier-Stokes; numerical method; lift force; raised panel method; discrete Fourier transform; collocation point shift; potential flow; CFD; free surface; induced drag; SHIPFLOW; dispersion; damping; analytical method; hydrofoil;

   Abstract : Two non-linear Rankine-source panel methods are developed and implemented in the same computer code. The first method uses a four-point upwind operator on the free-surface to compute the velocity derivatives and to enforce the radiation condition while the second method uses an analytical expression for the velocity derivatives and a collocation point shift one panel upstream to prevent upstream waves. READ MORE

5. 3. Statistical analysis of gene expression data

   Author : Erik Kristiansson; Göteborgs universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; gene expression; DNA microarrays; linear models; empirical Bayes; quality control; gene regulation; categorical data analysis; logistic regression; heavy metal stress; ecotoxicology; gene expression;

   Abstract : Microarray technology has become one of the most important tools for genome-wide mRNA measurements. The technique has been successfully applied to many areas in modern biology including cancer research, identification of drug targets, and categorization of genes involved in the cell cycle. READ MORE

6. 4. Targeted analysis of bioactive steroids and oxycholesterols : Method development and application

   Author : Neil de Kock; Jonas Bergquist; Ulf Diczfalusy; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Steroids; Oxycholesterols; Supercritical Fluid Chromatography; Mass Spectrometry; Kemi med inriktning mot analytisk kemi; Chemistry with specialization in Analytical Chemistry;

   Abstract : Peripheral steroids and oxycholesterols are important lipid compounds controlling various functions in the human body. Steroid analysis of biological samples is routinely employed in the clinical environment as an essential source of information on endocrine and metabolic disorders. READ MORE

7. 5. Gene expression in carcinogenesis

   Author : Heléne Fischer; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : It is important to understand the processes of carcinogenesis and to find out which genes are involved . One way to study the process on a molecular basis is to identify differences in gene expression. READ MORE