Search for dissertations about: "extrinsic allergic alveolitis"

Found 2 swedish dissertations containing the words extrinsic allergic alveolitis.

  1. 1. Inflammatory mechansims in pulmonary sarcoidosis

    Author : Mary Berlin; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Adhesion molecules; alveolitis; bronchoalveolar lavage; bronchial hyperreactivity; extracellular matrix molecules; extrinsic allergic alveolitis; fibrosis; HLA-DR; sarcoidosis; TCR;

    Abstract : Pulmonary sarcoidosis is an inflammatory disorder of unknown aetiology, characterised by an accumulation of CD4+ T-cells in the alveolar compartment and by granuloma formation and varying degrees of interstitial fibrosis. The initial clinical presentation may either be acute with fever, malaise, arthritis and/or erythema nodosum or insidious with cough, dyspnea, tiredness, and loss of weight. READ MORE

  2. 2. T cell antigen receptor usage, phenotype and cytokine production in human diseases

    Author : Jan Wahlström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : T cell; T cell receptor; T cell expansion; phenotype; cytokine; extrinsic allergic alveolitis; allergic asthma; multiple myeloma; Wegener s granulomatosis; sarcoidosis;

    Abstract : T lymphocytes are of critical importance for initiating and controlling immune responses, as the T cell receptor (TCR) for antigen allows a highly specific antigen recognition. Determination of TCR usage and characterization of T cell subsets in different diseases helps us understand the underlying immunopathogenic mechanisms, and may also lead to the development of new therapeutic approaches. READ MORE