Search for dissertations about: "factors perfusion"

Showing result 1 - 5 of 85 swedish dissertations containing the words factors perfusion.

2. 1. Quantitative Tracer Based MRI Perfusion : Potentials and Limitations

   Author : Arvid Morell; Atle Bjørnerud; Håkan Ahlström; Linda Knutsson; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MRI; Perfusion; Contrast agent; Relaxivity; Radiology; Radiologi;

   Abstract : Tracer based MRI perfusion measurements is a clinically useful tool to assess regional distributions of tissue blood flow and volume. The method may be based on any of the three relaxation mechanisms T1, T1 and T2*, the latter denoted DSC-MRI being the most common. READ MORE

4. 2. Placental Function : An Epidemiological and Magnetic Resonance Study

   Author : Sara Sohlberg; Anna-Karin Wikstrom; Matts Olovsson; Ajlana Mulic-Lutvica; Johan Wikström; Karel Marsal; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; body height; body mass index; early preeclampsia; late preeclampsia; magnetic resonance imaging; placenta; perfusion; IVIM; risk factors; energy metabolism; magnetic resonance spectroscopy; 31P-MRS; Obstetrik och gynekologi; Obstetrics and Gynaecology;

   Abstract : Placental function is central for normal pregnancy and in many of the major pregnancy disorders. We used magnetic resonance imaging techniques to investigate placental function in normal pregnancy, in early and late preeclampsia and in intrauterine growth restriction. READ MORE

5. 3. Optimisation and Validation of Dynamic Susceptibility Contrast MRI Perfusion Measurements

   Author : Linda Knutsson; Lund Medicinsk strålningsfysik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nukleärmedicin; radiobiologi; Nuclear medicine; radiobiology; radiologi; tomografi; medicinsk instrumentering; tomography; medical instrumentation; Clinical physics; cerebral blood volume; mean transit time; cerebral blood flow; perfusion; dynamic susceptibility contrast MRI arterial input function; Klinisk fysiologi; radiology;

   Abstract : The studies presented in this thesis concern the optimisation and evaluation of the dynamic susceptibility contrast magnetic resonance imaging (DSC-MRI) technique for the assessment of perfusion-related parameters of the brain, such as cerebral blood flow (CBF), cerebral blood volume (CBV) and mean transit time (MTT). Several methodological factors influence these measurements, for example, contrast-agent administration, arterial input function (AIF) registration, choice of deconvolution algorithm and the choice of pulse-sequence parameters. READ MORE

6. 4. Isolated regional perfusion for metastases of malignant melanoma - Clinical and experimental studies

   Author : Roger Olofsson; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Malignant melanoma; Uveal melanoma; Isolated limb perfusion; Isolated hepatic perfusion; Immunology; Exosomes;

   Abstract : Background: Isolated regional perfusion is a treatment option mainly for localized metastatic disease. The principle idea is to surgically isolate a region of the body and connect the circulation to a heart-lung machine. A high concentration of a chemotherapeutic agent is then delivered to the tumour, while systemic toxicity is avoided. READ MORE

7. 5. Development of mathematical modelling for the glycosylation of IgG in CHO cell cultures

   Author : Liang Zhang; Véronique Chotteau; Michael J. Betenbaugh; KTH; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Chinese hamster ovary cells; glycosylation; IgG; mathematical modelling; experimental design; perfusion; carbon sources; GReBA; Bayesian network; probabilistic graphic model; Bioteknologi; Biotechnology;

   Abstract : Chinese hamster ovary (CHO) cells are the most popular expression system for the production of biopharmaceuticals. More than 80% of the approved monoclonal antibodies (mAbs) or immunoglobulin G (IgG) are produced with these cells. Glycosylation is a usual post- translational modification important for therapeutic mAbs. READ MORE