Search for dissertations about: "fibroblast growth factor 2"

Showing result 1 - 5 of 83 swedish dissertations containing the words fibroblast growth factor 2.

  2. 1. Regulation of Fibroblast Activity by Keratinocytes

    Author : Daniel Nowinski; Mikael Ivarsson; Bengt Gerdin; Elof Ph D M.D. Eriksson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; conective tissue growth factor; interleukin-1; fibroblast; keratinocyte; wound healing; burns; Kirurgi; Surgery; Kirurgi;

    Abstract : In the healing of cutaneous wounds, paracrine communication between keratinocytes and fibroblasts regulates cell differentiation, proliferation and synthesis of extracellular matrix. Deficient epidermal coverage, as seen in burn-wounds, frequently results in hypertrophic scars. READ MORE

  4. 2. Fibroblast growth factor-induced signal transduction

    Author : Peter Klint; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Biokemi; Biochemistry; Biokemi; molekylär cellbiologi; Molecular Cellbiology;

    Abstract : Fibroblast growth factors (FGFs) evoke cellular responses by binding to FGF receptors (FGFRs). FGFRs are cell surface expressed membrane-spanning receptors with intrinsic stimulatable tyrosine kinase activity. This thesis describes the cell proliferation or differentiation. READ MORE

  5. 3. Fibroblast Growth Factor Receptor-1 Function in Vasculo- and Angiogenesis

    Author : Peetra Magnusson; Lena Claesson-Welsh; Anne Eichmann; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; FGF; FGFR-1; VEGFR-2; PDGFR-β; endothelial cells; embryonic stem cell; angiogenesis; hematopoiesis; Patologi; Pathology; Patologi;

    Abstract : During development of the mammalian embryo, spatial and temporal expression of fibroblast growth factors (FGFs) and their cognate receptors are vital in the regulation of a number of patterning processes. Inappropriate or decreased expression leads to severe malformations and even embryonic death. READ MORE

  6. 4. Fibroblast growth factor-8 regulation of breast cancer cell growth

    Author : Emeli Nilsson; Institutionen för translationell medicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Expression of fibroblast growth factor-8 (FGF-8) is increased in a large number of breast cancers. In in vitro and in vivo breast cancer models FGF-8 promotes growth, invasion and angiogenesis. READ MORE

  7. 5. Search for Biomarkers in ALS and Parkinson's Disease : Positron Emission Tomography and Cerebrospinal Fluid Studies

    Author : Anders Johansson; Håkan Askmark; Lennart Persson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; amyotrophic lateral sclerosis; ALS; Parkinson’s disease; cerebrospinal fluid; positron emission tomography; vascular endothelial growth factor; fibroblast growth factor 2; proteomics; Fourier transform ion cyclotron resonance mass spectrometry; deprenyl-D2; PIB; FDG; L-[β11C]-DOPA; Neurology; Neurologi; Neurology; neurologi;

    Abstract : New biomarkers are needed to improve knowledge about pathophysiology, in order to provide earlier correct diagnosis and to follow disease progression of the neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and Parkinson's disease (PD). The aim of this thesis was to find new biomarkers for these diseases. READ MORE