Search for dissertations about: "flow cytometry phagocytosis"

Showing result 1 - 5 of 9 swedish dissertations containing the words flow cytometry phagocytosis.

  2. 1. The adenoid defender of the nasopharynx. A study of the cells in the surface secretion in the nasopharynx

    Author : Magnus Ivarsson; Göteborgs universitet; []
    Keywords : Adenoid; nasopharynx; leukocytes; surface secretion; ELISPOT; phagocytosis;

    Abstract : The adenoid is implicated in the pathogenesis of upper airway infections (UAI), but in a not yet understood way. In contrast to the adenoid tissue, the surface secretion on the adenoid, which contains not only pathogenic bacteria and viruses but also leukocytes, has attracted little interest. READ MORE

  4. 2. Eosinophil Apoptosis

    Author : Kristina Seton; Joachim Lundahl; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell biology; Apoptosis; Programmed Cell Death; Survival; Eosinophils; Inflammatory Diseases; Resolution of inflammation; Functions; Flow cytometry; Cellbiologi; Cell biology; Cellbiologi; Clinical Chemistry; klinisk kemi;

    Abstract : Apoptosis or programmed cell death is crucial for the resolution of inflammation, and phagocytosis of apoptotic cells initiates the release of actively anti-inflammatory responses from the phagocytes. Eosinophils are one of the most potent inflammatory cells in the body and is involved in a number of diseases, most commonly associated with parasitic infections and allergic diseases. READ MORE

  5. 3. Role of GPIbαlpha Clustering and N-linked Carbohydrates in the Clearance of Refrigerated Platelets

    Author : Emma Josefsson; Göteborgs universitet; []
    Keywords : Platelets; GPIbalpha; alphaMbeta2; phagocytosis; refrigerated platelets;

    Abstract : The thesis focuses on understanding the mechanisms by which: 1) the macrophage alphaM-subunit recognizes betaN-acetylglucosamine (betaGlcNAc) residues on the von Willebrand factor receptor complex ((GPIbalpha,beta/IX)2V or vWfR) on refrigerated platelets and 2) refrigeration changes vWfR to elicit recognition through alphaMbeta2. Until recently, the only well-established mechanisms affecting platelet survival were antibody-mediated platelet clearance, consumption of platelets by coagulation reactions, and loss due to massive bleeding. READ MORE

  6. 4. Commensal microbes, immune reactivity and childhood inflammatory bowel disease

    Author : Cecilia Barkman; Göteborgs universitet; []
    Keywords : Inflammatory bowel disease; IBD; Pediatric; Childhood; Microbiota; T cells; B cells; cytokine; IL-12; monocytes; phagocytosis; intracellular signaling pathway; Crohn s disease; ulcerative colitis; children; flora;

    Abstract : Inflammatory bowel disease (IBD) is characterized by chronic and relapsing intestinal inflammation of unknown etiology, but immune activation by the commensal microbiota probably plays a major role. The two major categories of IBD are ulcerative colitis and Crohn’s disease. READ MORE

  7. 5. Development and evaluation of immunoassays for complement diagnostics

    Author : Kerstin Sandholm; Kristina Nilsson Ekdahl; Ingvar Ryden; Linnéuniversitetet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immune assays; complement diagnostics; xMAP-technology; C1q; preanalytical factors; method validation; Immunologi; Immunology;

    Abstract : Laboratory analyses of human body fluids play an important role in clinical diagnosis. This thesis comprises projects in which various immune assays have been developed and evaluated as complement diagnostics in both plasma and cerebrospinal fluid (CSF). READ MORE