Search for dissertations about: "focal adhesion complex"
Showing result 1 - 5 of 16 swedish dissertations containing the words focal adhesion complex.
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1. Regulation of the cytoskeleton and the adhesiveness of intestinal epithelial cells by leukotriene D4
Abstract : Leukotrienes belong to a family of biologically active conjugated trienes that are formed from arachidonic acid via the 5-lipoxygenase pathway and are important mediators of inflammatory reactions. The CysLT1 receptor that specifically serves as receptor for leukotriene D4 (LTD4) has been identified as a G-protein coupled receptor. READ MORE
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2. Molecular Mechanisms of Action of Histidine-rich Glycoprotein in Angiogenesis Inhibition
Abstract : Angiogenesis, de novo synthesis of blood vessels from the pre-existing vasculature, is required both during embryonic development and in pathophysiological conditions. In particular, tumor growth needs new capillary vessels in order to both deliver oxygen and nutrients and to remove toxin and metabolites. READ MORE
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3. Mechanisms of HAMLET-induced cancer cell death
Abstract : HAMLET, a complex of α-lactalbumin and oleic acid, preferentially kills cancer cells and is also effective in vivo. HAMLET causes apoptosis but cells die even if this pathway is inhibited. Thus, the role of autophagy, an alternative cell death pathway, was examined. READ MORE
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4. Integrating bioinformatics and physiology to describe genetic effects in complex polygenic diseases
Abstract : Type 2 diabetes mellitus (T2DM) results from interaction between genetic and environmental factors. The worldwide prevalence of T2DM is increasing rapidly due to reduction in physical activity, increase in dietary intake, and the aging of the population. READ MORE
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5. Nitric oxide in exhaled gas : studies on physiological regulation and measurements in infants and children
Abstract : Nitric oxide (NO) is found in the exhaled gas of humans, starting from birth, and is increased in adult patients with bronchial asthma. This study assessed whether the measurement of NO in exhaled gas is technically feasible in infants and children. READ MORE