Search for dissertations about: "gait"

Showing result 1 - 5 of 211 swedish dissertations containing the word gait.

  2. 1. Structures, toxicity and internalization of cell-penetrating peptides

    Author : Emelía Eiríksdóttir; Ülo Langel; Michael Gait; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CPP; cell-penetrating peptide; internalization; toxicity; structures; Neurochemistry; Neurokemi; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Abstract : Cellular internalization is a highly regulated process controlled by proteins in the plasma membrane. Large and hydrophilic compounds, in particular, face difficulties conquering the plasma membrane barrier in order to gain access to intracellular environment. This puts serious constrains on the drug industry since many drugs are hydrophilic. READ MORE

  4. 2. Cell-penetrating peptides in protein mimicry and oligonucleotide delivery : Applications and mechanisms

    Author : Henrik Johansson; Ülo Langel; Michael Gait; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; peptide; oligonucleotide; cell-penetrating peptide; PNA; splicing; Neurochemistry; Neurokemi; Neurochemistry and Molecular Neurobiology; neurokemi med molekylär neurobiologi;

    Abstract : The plasma membrane functions as a barrier, restricting entry of hydrophilic pharmaceutical agents. Cell-penetrating peptides (CPPs) are capable of transporting bioactive cargos into the cell and have consequently been extensively investigated for their mechanism of entry and capability to deliver various cargos spanning from peptides to plasmids. READ MORE

  5. 3. Cell-penetrating peptides and bioactive cargoes : Strategies and mechanisms

    Author : Kalle Kilk; Ülo Langel; Michael J. Gait; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell-penetrating peptide; delivery; Peptide nucleic acid; Biochemistry; Biokemi;

    Abstract : The cell membrane is an impermeable barrier for most macromolecules. Recently discovered cell-penetrating peptides (CPPs) have gained lot of attention because they can cross the membrane, and even more, carry cargoes with them. How CPPs enter cells is still not clear, while the delivery of different cargoes has been convincingly shown. READ MORE

  6. 4. Objective and subjective aspects related to walking in people with neurodegenerative disorders

    Author : Magnus Lindh-Rengifo; Aktivt och hälsosamt åldrande; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neurodegenerative disorders; parkinson s disease; mild cognitive impairment; gait; walking; perceived walking difficulties; concerns about falling; Neurodegenerative disorders; Parkinson s disease; Mild cognitive impairment; Gait; Walking; Perceived walking difficulties; Concerns about falling;

    Abstract : .... READ MORE

  7. 5. Knee flexion contracture and flexed knee gait in children with cerebral palsy

    Author : Evelina Pantzar-Castilla; Jacques Riad; Per Wretenberg; Piotr Michno; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cerebral palsy; knee flexion contracture; 2- and 3-dimensional gait analysis; video assessment; gait; flexed knee gait; functional measures; orthopedic surgery;

    Abstract : Cerebral palsy (CP) is considered the most common cause of physical disability in childhood. Most children will walk, but gait often deteriorates with growth and development. READ MORE