Search for dissertations about: "galantamine"
Showing result 1 - 5 of 11 swedish dissertations containing the word galantamine.
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1. Functional brain activity in Alzheimer patients as studied by multi-tracer positron emission tomography : effects of treatment with cholinesterase inhibitors
Abstract : Alzheimer’s disease (AD) is a progressive neurodegenerative disease accompanied by cognitive impairment and disturbances in several neurotransmitter systems, especially the cholinergic system. Studies have correlated the cognitive impairment observed in AD patients with a deficit in central cholinergic neurotransmission. READ MORE
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2. Regulatory mechanisms and plasticity of nicotinic receptors in transgenic mice overexpressing human beta-amyloid (APPswe) and acetylcholinesterase : implications for Alzheimer’s disease
Abstract : Alzheimer’s disease (AD) is the most frequent type of dementia and is characterized neuropathologically by deposition of plaques containing beta-amyloid (Abeta) and by neurofibrillary tangles, of which the main component is hyperphosphorylated tau. The degenerative progression seen in AD is accompanied by disturbances in several neurotransmitter systems, especially the cholinergic neurotransmitter system. READ MORE
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3. Long Term Outcome and Prediction Models of Cognition, Activities of Daily Living and Nursing Home Placement in Alzheimer’s Disease with Cholinesterase Inhibitor Treatment
Abstract : Background Prospective longitudinal studies in Alzheimer's disease (AD) that include cholinesterase inhibitor (ChEI) treatment in routine clinical settings are scarce. The patients vary in severity of the disease, clinical course, rate of progression and response to treatment. READ MORE
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4. Using CSF biomarkers to understand mechanisms of behavioral changes and effects of drug treatment in dementia
Abstract : Dementia is affecting millions of people around the world, and the global prevalence will continuously rise. Neuropsychiatric symptoms (NPS) in dementia are frequent and constitute a key driving force in the disease burden for both patients, families, caregivers and society. READ MORE
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5. Novel pharmacological treatment alternatives for schizophrenia
Abstract : Antipsychotic drugs are commonly divided into typical (first generation) and atypical (second generation) antipsychotic drugs. Clinically effective doses of typical antipsychotic drugs generate a striatal dopamine D2 receptor occupancy of about 70 80%, approaching a level that is associated with a high risk of extrapyramidal side effects. READ MORE