Search for dissertations about: "galectin-3"
Showing result 1 - 5 of 41 swedish dissertations containing the word galectin-3.
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1. Galectin-3 Ligand Binding: Mechanism and Driving Forces
Abstract : .... READ MORE
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2. Functional properties of galectin-3. Beyond the sugar binding
Abstract : Contemporary diseases like diabetes, asthma, atherosclerosis etc. are marked by chronic inflammation, often supported by the activity of different macrophages. Proteins from galectin family were found to contribute to disease pathophysiology. Therefore, there is an intensive interest in understanding different galectin functions. READ MORE
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3. Microglial cells in Neurodegenerative Diseases. The Role of Galectin-3
Abstract : Today, dementia such as, Alzheimer’s disease (AD), vascular diseases and motor neurodegenerative diseases, such as Parkinson’s disease (PD), represent a major public health problem. For instance, PD affect to more than 10 million people worldwide and almost 50 million people are affected by dementia. READ MORE
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4. Neutrophil function in health and disease - role of intracellular radicals and galectin-3 as regulators of inflammation
Abstract : The focus for this PhD project has been to investigate neutrophil functions in different (inflammatory) settings with specific focus on phagocyte-derived intracellular reactive oxygen species (ROS) as well as neutrophil interaction with the inflammatory mediator galectin-3. Neutrophils, the most abundant leukocyte in human blood, have traditionally been viewed upon mainly as professional phagocytes, being able to degrade invading microbes, and thus essential in the defence against infection. READ MORE
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5. Inflammation in experimental neonatal brain injury and in a clinical study of preterm birth; involvement of galectin-3 and free radical formation
Abstract : Introduction; Intrauterine infection/inflammation is associated with preterm delivery (PTD) and severe neonatal morbidity. Inflammation is also important in the secondary neurotoxic cascade leading to perinatal brain injury. READ MORE